Evidence map›Paper›PMID 35265194›Full record

ArticleTheranostics2022

Characterization and modulation of surface charges to enhance extracellular vesicle isolation in plasma.

Hyun-Kyung Woo, Young Kwan Cho, Chang Yeol Lee, Haeun Lee, Cesar M Castro, Hakho Lee

Abstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Extracellular vesicles in colorectal cancer.Annals of coloproctology · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyun-Kyung WooCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Young Kwan ChoCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Chang Yeol LeeCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Haeun LeeCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Cesar M CastroCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Hakho LeeCenter for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Funding

Early Detection through Novel OCEAN Technology - Ovarian Cancer Exosomal Analysis with NanoplasmonicsU01CA233360 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CASTRO, CESAR M, DINULESCU, DANIELA M · 2018 to 2022
$3.5M
Clinical platform for high-throughput analyses of extracellular vesiclesR01CA229777 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO, SKOG, JOHAN · 2018 to 2022
$3.2M
Imaging and Liquid Biopsy for Glioma Diagnosis and Treatment MonitoringR01CA239078 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BALAJ, LEONORA, LEE, HAKHO · 2020 to 2024
$3.1M
Standardized Molecular Analyses of Glioma EVsR01CA237500 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CARTER, BOB S, LEE, HAKHO · 2020 to 2024
$3.0M
High throughput nanoplasmonic exosome testing (NEXT) of immunotherapies in bladder cancerR01CA264363 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CASTRO, CESAR M, LEE, HAKHO · 2021 to 2024
$2.4M
High-throughput Integrated Magneto-electrochemical Exosome (HiMEX) platform to identify neurodevelopmental markers associated with pre and postnatal oxycodone exposureR21DA049577 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI LEE, HAKHO, PENDYALA, GURUDUTT · 2019 to 2020
$458k
NCI NIH HHS R01 CA229777NCI NIH HHS R01 CA237500NCI NIH HHS R01 CA239078NCI NIH HHS R01 CA264363NCI NIH HHS U01 CA233360NIDA NIH HHS R21 DA049577
6 · The paper itself

Abstract

Extracellular vesicles (EVs) carry information inherited from parental cells, having significant potential for disease diagnosis. In blood, however, EVs are outnumbered >10

Indexed as

Extracellular VesiclesLipoproteins, LDLPlasmaProteomicsRNA, MessengerLipoproteins, LDLRNA, Messengercancerextracellular vesicleslipoproteinssize-exclusionsurface charge modulation

Identifiers

PMID35265194
PMCPMC8899565

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.