Evidence map›Paper›PMID 35265090›Full record

ArticleFrontiers in immunology2022

Transcriptome Profiling of Porcine Naïve, Intermediate and Terminally Differentiated CD8

Emil Lagumdzic, Clara Pernold, Marta Viano, Simone Olgiati, Michael W Schmitt, Kerstin H Mair, Armin Saalmüller

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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  7. Single-cell transcriptome analysis of the mouse lungs during the injury and recovery periods after lipopolysaccharide administration.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Emil LagumdzicDepartment of Pathobiology, Institute of Immunology, University of Veterinary Medicine, Vienna, Austria.
Clara PernoldDepartment of Pathobiology, Institute of Immunology, University of Veterinary Medicine, Vienna, Austria.
Marta VianoIstituto di Ricerche Biomediche "A. Marxer" RBM S.p.A., Torino, Italy.
Simone OlgiatiIstituto di Ricerche Biomediche "A. Marxer" RBM S.p.A., Torino, Italy.
Michael W SchmittMerck Healthcare KGaA, Chemical & Preclinical Safety, Darmstadt, Germany.
Kerstin H MairDepartment of Pathobiology, Institute of Immunology, University of Veterinary Medicine, Vienna, Austria.
Armin SaalmüllerDepartment of Pathobiology, Institute of Immunology, University of Veterinary Medicine, Vienna, Austria.
University of Veterinary Medicine Vienna · ATMerck (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pig has the potential to become a leading research model for human diseases, pharmacological and transplantation studies. Since there are many similarities between humans and pigs, especially concerning anatomy, physiology and metabolism, there is necessity for a better understanding of the porcine immune system. In adaptive immunity, cytotoxic T lymphocytes (CTLs) are essential for host defense. However, most data on CTLs come from studies in mice, non-human primates and humans, while detailed information about porcine CD8

Indexed as

CD8-Positive T-LymphocytesLymphocyte ActivationAnimalsGene Expression ProfilingIonomycinMiceSwineT-Lymphocyte SubsetsIonomycinCD8+ T cellsRNA-SeqswineT-cell differentiationtranscriptome

Identifiers

PMID35265090
PMCPMC8900158
OpenAlexW4213386158

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.