Evidence map›Paper›PMID 35265028›Full record

ArticleFrontiers in neurology2022

Brain Activity Changes in Slow 5 and Slow 4 Frequencies in Patients With Optic Neuritis: A Resting State Functional MRI Study.

Kai Yan, Wen-Qing Shi, Ting Su, Xu-Lin Liao, Shi-Nan Wu, Qiu-Yu Li, Jing Yu, Hui-Ye Shu, Li-Juan Zhang, Yi-Cong Pan and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Kai YanDepartment of Radiology, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
Wen-Qing ShiDepartment of Ophthalmology, Jiangxi Centre of National Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Ting SuDepartment of Ophthalmology, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, United States.
Xu-Lin LiaoDepartment of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Shi-Nan WuDepartment of Ophthalmology, Jiangxi Centre of National Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Qiu-Yu LiDepartment of Ophthalmology, Jiangxi Centre of National Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jing YuDepartment of Acupuncture and Moxibustion, Hangzhou TCM Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, China.
Hui-Ye ShuDepartment of Ophthalmology, Jiangxi Centre of National Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Li-Juan ZhangDepartment of Ophthalmology, Jiangxi Centre of National Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yi-Cong PanDepartment of Ophthalmology, Jiangxi Centre of National Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yi ShaoDepartment of Ophthalmology, Jiangxi Centre of National Clinical Ophthalmology Institute, The First Affiliated Hospital of Nanchang University, Nanchang, China.
First Affiliated Hospital of Nanchang University · CNNanchang University · CNZhejiang Chinese Medical University · CNChinese University of Hong Kong · CNMassachusetts Eye and Ear Infirmary · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We used the amplitude of low-frequency fluctuation (ALFF) method to investigate spontaneous brain activity in patients with optic neuritis (ON) in specific frequency bands. Data and Methods: A sample of 21 patients with ON (13 female and eight male) and 21 healthy controls (HCs) underwent functional magnetic resonance imaging (fMRI) scans in the resting state. We analyzed the ALFF values at different frequencies (slow-4 band: 0.027-0.073 Hz; slow-5 band: 0.01-0.027 Hz) in ON patients and HCs. Results: In the slow-4 frequency range, compared with HCs, ON patients had apparently lower ALFF in the insula and the whack precuneus. In the slow-5 frequency range, ON patients showed significantly increased ALFF in the left parietal inferior and the left postcentral. Conclusion: Our results suggest that ON may be involved in abnormal brain function and can provide a basis for clinical research.

Indexed as

amplitude of low-frequency fluctuationfunctional magnetic resonance imagingoptic neuritisresting stateslow 5 and slow 4 frequencies

Identifiers

PMID35265028
PMCPMC8900534
OpenAlexW4213060709

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.