Evidence map›Paper›PMID 35264793›Full record

ArticleNature2022

Cortical processing of flexible and context-dependent sensorimotor sequences.

Duo Xu, Mingyuan Dong, Yuxi Chen, Angel M Delgado, Natasha C Hughes, Linghua Zhang, Daniel H O'Connor

Open access · greenAbstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Whisker-based pre-neuronal and peripheral encoding of surface stickiness.bioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Integration of Memory and Sensory Information in Skilled Sequence Production.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Dynamic engagement of the motor cortex in controlling movement.bioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Duo XuThe Solomon H. Snyder Department of Neuroscience, Krieger Mind/Brain Institute, Kavli Neuroscience Discovery Institute, Brain Science Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mingyuan DongThe Solomon H. Snyder Department of Neuroscience, Krieger Mind/Brain Institute, Kavli Neuroscience Discovery Institute, Brain Science Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID http://orcid.org/0000-0001-9120-1315
Yuxi ChenUndergraduate Studies, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-7826-4212
Angel M DelgadoUndergraduate Studies, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.
Natasha C HughesUndergraduate Studies, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, MD, USA.
Linghua ZhangThe Solomon H. Snyder Department of Neuroscience, Krieger Mind/Brain Institute, Kavli Neuroscience Discovery Institute, Brain Science Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Daniel H O'ConnorThe Solomon H. Snyder Department of Neuroscience, Krieger Mind/Brain Institute, Kavli Neuroscience Discovery Institute, Brain Science Institute, The Johns Hopkins University School of Medicine, Baltimore, MD, USA. dan.oconnor@jhmi.edu.ORCID http://orcid.org/0000-0002-9193-6714
Allen Institute for Brain Science · USJohns Hopkins University · US

Funding

Murine Mutagenesis CoreP30NS050274 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KOLODKIN, ALEX L · 2005 to 2020
$10.9M
Norepinephrine modulation of neocortex during flexible behaviorR01NS104834 · NINDS · JOHNS HOPKINS UNIVERSITY · PI COHEN, JEREMIAH YAACOV, O'CONNOR, DANIEL HANS · 2018 to 2022
$4.1M
Circuit and cellular dynamics in mouse cortex during tactile detectionR01NS089652 · NINDS · JOHNS HOPKINS UNIVERSITY · PI O'CONNOR, DANIEL HANS · 2014 to 2019
$2.1M
NINDS NIH HHS P30 NS050274NINDS NIH HHS R01 NS089652NINDS NIH HHS R01 NS104834
6 · The paper itself

Abstract

The brain generates complex sequences of movements that can be flexibly configured based on behavioural context or real-time sensory feedback

Indexed as

Motor CortexMovementAnimalsMiceOptogeneticsSomatosensory CortexTongueTouch

Identifiers

PMID35264793
PMCPMC9109820
OpenAlexW4220757519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.