Evidence map›Paper›PMID 35264791›Full record

ArticleNature2022

Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue.

Federico Cerullo, Sebastian Filbeck, Pratik Rajendra Patil, Hao-Chih Hung, Haifei Xu, Julia Vornberger, Florian W Hofer, Jaro Schmitt, Guenter Kramer, Bernd Bukau and 3 more

Abstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Translation factors that keep the ribosome Pro-active.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Collided ribosomes are rescued by the endonuclease Rae1 andbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Ribosome-associated quality control and related mechanisms.Nature structural & molecular biology · 2026
    Review
  6. Article
  7. Article
  8. Plant MutS2 proteins function in plastid ribosome quality control.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Federico Cerullo *Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6042-7810
Sebastian Filbeck *Zentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-5729-4538
Pratik Rajendra PatilZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.
Hao-Chih HungZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.
Haifei XuDepartment of Molecular Medicine, Scripps Florida, Jupiter, FL, USA.
Julia VornbergerZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.
Florian W HoferZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6531-3820
Jaro SchmittZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6701-7112
Guenter KramerZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-7552-8393
Bernd BukauZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-0521-7199
Kay HofmannInstitute for Genetics, University of Cologne, Cologne, Germany.ORCID http://orcid.org/0000-0002-2289-9083
Stefan PfefferZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany. s.pfeffer@zmbh.uni-heidelberg.de.ORCID http://orcid.org/0000-0001-5843-2795
Claudio A P JoazeiroZentrum für Molekulare Biologie der Universität Heidelberg, DKFZ-ZMBH Alliance, Heidelberg, Germany. c.joazeiro@zmbh.uni-heidelberg.de.ORCID http://orcid.org/0000-0003-1433-8013

Funding

Polyalanine Tails: A Novel Type of Protein Modification Implicated in NeurodegenerationR01NS102414 · NINDS · JACKSON LABORATORY · PI Robert W. Burgess, GREGORY A. COX · 2017 to 2026
$7.0M
NINDS NIH HHS R01 NS102414
6 · The paper itself

Abstract

Ribosome stalling during translation is detrimental to cellular fitness, but how this is sensed and elicits recycling of ribosomal subunits and quality control of associated mRNA and incomplete nascent chains is poorly understood

Indexed as

Adenosine TriphosphatasesRibosomesBacillus subtilisCryoelectron MicroscopyDNA RepairProtein BiosynthesisProteinsAdenosine TriphosphatasesProteins

Identifiers

PMID35264791
PMCPMC9041291

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.