ArticleNature2022
Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
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Who cites it
74 citing papers in PubMed, 113 citations in OpenAlex.
- Pyrrolysine supply and demand shapes the translational landscape inProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Translation factors that keep the ribosome Pro-active.Microbiology and molecular biology reviews : MMBR · 2026Review
- Collided ribosomes are rescued by the endonuclease Rae1 andbioRxiv : the preprint server for biology · 2026Article
- Blocked transcription-translation complexes are rescued by transcript release followed byJournal of bacteriology · 2026Article
- The alarmone pGpp inhibits translation through GTP depletion.Nucleic acids research · 2026Article
- Synthesis of Ultra-Large Fibrous Proteins from Bacteria via a Looped-Translation System.bioRxiv : the preprint server for biology · 2026Article
- The transcriptional and translational outcomes for pseudogenes in bacterial endosymbionts.Molecular biology and evolution · 2026Article
- Coordinated translation initiation determines -1 programmed ribosomal frameshifting efficiency of chromosomal genes to impact on cell fitness.The FEBS journal · 2026Article
- Mechanism of RACK1-dependent ZAKα activation at stalled and collided ribosomes.Molecular cell · 2026Article
- Harnessing toxin-mediated ribosome stalling as a complementary tool to annotate bacterial ORFs.Nucleic acids research · 2026Article
- Stoichiometry-induced differential selection on codon optimization among ribosomal protein genes in bacterial species.Molecular biology and evolution · 2026Article
- Article
- Starvation-independent alarmone production inhibits translation through GTP depletion.bioRxiv : the preprint server for biology · 2026Article
- Translation quality control in Pseudomonas aeruginosa: current knowledge and perspectives.FEMS microbiology reviews · 2026Review
- AI-powered mapping of tumor immunity for optimized mRNA vaccine engineering.Frontiers in oncology · 2026Review
- Structure of the 30S translation initiation complex coupled to paused RNA polymerase and its potential for riboregulation.Nature communications · 2025Article
- Carrot and stick: how RNase R contributes to function and destruction of the translation machinery.RNA biology · 2025Review
- Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli.Nucleic acids research · 2025Article
- CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice.Science translational medicine · 2025Article
- Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality control.Nature structural & molecular biology · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Kazuki Saito *Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA.
Hanna Kratzat *Gene Center and Department of Biochemistry, University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0001-5849-6131
Annabelle CampbellDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA.
Robert BuschauerGene Center and Department of Biochemistry, University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-5794-4841
A Maxwell BurroughsComputational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, USA.ORCID http://orcid.org/0000-0002-2229-8771
Otto BerninghausenGene Center and Department of Biochemistry, University of Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-9255-0522
L AravindComputational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, USA.
Rachel GreenDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA.ORCID http://orcid.org/0000-0001-9337-2003
Roland BeckmannGene Center and Department of Biochemistry, University of Munich, Munich, Germany. beckmann@genzentrum.lmu.de.ORCID http://orcid.org/0000-0003-4291-3898
Allen R BuskirkDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA. buskirk@jhmi.edu.ORCID http://orcid.org/0000-0003-2720-6896
Johns Hopkins University · USNational Institutes of Health · USGene Therapy Laboratory · FRHoward Hughes Medical Institute · US
Funding
BIOCHEMISTRY, CELLULAR AND MOLECULAR BIOLOGY PROGRAMT32GM007445 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 1985 to 2021
$24.1MEvolutionary Analysis and Comparative Genomics of Protein SuperfamiliesZIALM594244 · NLM · NATIONAL LIBRARY OF MEDICINE · PI ARAVIND, L · 2009 to 2025
$20.3MMolecular mechanisms of ribosome pausing and the cellular responseR37GM059425 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GREEN, RACHEL · 2014 to 2023
$3.5MThe role of collisions in rescuing stalled ribosomes in bacteriaR01GM136960 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Allen Rowdon Buskirk · 2021 to 2026
$1.9MNIGMS NIH HHS R01 GM136960NIGMS NIH HHS R37 GM059425NIGMS NIH HHS T32 GM007445
Abstract
Ribosome rescue pathways recycle stalled ribosomes and target problematic mRNAs and aborted proteins for degradation
Indexed as
Escherichia coliRibosomesBacteriaCryoelectron MicroscopyProtein BiosynthesisRNA, BacterialRNA, MessengerRNA, BacterialRNA, Messenger
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.