SynthesisScientific reports2022
Genomic evolution and adaptation of arthropod-associated Rickettsia.
Synthesis in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed, 71 citations in OpenAlex.
- Molecular Surveillance Reveals Diverse Tick-Borne Pathogens in Northern California.Pathogens (Basel, Switzerland) · 2026Article
- Pangenomic and genomic plasticity analyses of the genus Rickettsia.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Rickettsia massiliae and its public health significance across Palearctic and Oriental regions: a scoping review.Infectious diseases of poverty · 2026Article
- Molecular detection of Rickettsia rhipicephali and hemotropic Mycoplasma sp. in Dermacentor panamensis from a Mexican Hairy Dwarf Porcupine (Coendou mexicanus) in Veracruz, Mexico.Veterinary research communications · 2026Article
- Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility.The Journal of cell biology · 2026Article
- Analysis of the genomes of a male-killingMicrobial genomics · 2026Article
- Prevalence and Species Diversity of Spotted Fever Group Rickettsiae in Ixodid Ticks Collected in Northwest Russia.Tropical medicine and infectious disease · 2026Article
- Case Report: Effective use of omadacycline in Japanese spotted fever.Frontiers in medicine · 2026Article
- Spatial Heterogeneity of Tick-Borne Pathogens Outpaces Genetic Structuring in Anatolian Dermacentor reticulatus Populations.Transboundary and emerging diseases · 2026Article
- Bridging historical antigenic profiling and whole-genome taxonomy inScientific reviews · 2026Review
- Complete genomes of Rickettsia typhi reveal a clonal population.PLoS neglected tropical diseases · 2025Article
- Rickettsia spp. in finnish ixodid ticks.Parasites & vectors · 2025Article
- Ticks and Associated Rickettsiae from Domestic Animals in Bhutan.Pathogens (Basel, Switzerland) · 2025Article
- Mitogenomics of the tropical bont tick Amblyomma variegatum reveals vertical and horizontal transmission of Rickettsia africae.PLoS neglected tropical diseases · 2025Article
- Ecological Mercenaries: Why Aphids Remain Premier Models for the Study of Ecological Symbiosis.Insects · 2025Review
- Spatial Distribution of Equid Exposure toPathogens (Basel, Switzerland) · 2025Article
- A new spotted fever group Rickettsia genotype in Haemaphysalis leporispalustris from Maine, USA.Ticks and tick-borne diseases · 2025Article
- ThemBio · 2025Article
- Investigation of potentially zoonoticScience in One Health · 2025Article
- Molecular detection and characterization ofInfection ecology & epidemiology · 2025Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rickettsia species are endosymbionts hosted by arthropods and are known to cause mild to fatal diseases in humans. Here, we analyse the evolution and diversity of 34 Rickettsia species using a pangenomic meta-analysis (80 genomes/41 plasmids). Phylogenomic trees showed that Rickettsia spp. diverged into two Spotted Fever groups, a Typhus group, a Canadensis group and a Bellii group, and may have inherited their plasmids from an ancestral plasmid that persisted in some strains or may have been lost by others. The results suggested that the ancestors of Rickettsia spp. might have infected Acari and/or Insecta and probably diverged by persisting inside and/or switching hosts. Pangenomic analysis revealed that the Rickettsia genus evolved through a strong interplay between genome degradation/reduction and/or expansion leading to possible distinct adaptive trajectories. The genus mainly shared evolutionary relationships with α-proteobacteria, and also with γ/β/δ-proteobacteria, cytophagia, actinobacteria, cyanobacteria, chlamydiia and viruses, suggesting lateral exchanges of several critical genes. These evolutionary processes have probably been orchestrated by an abundance of mobile genetic elements, especially in the Spotted Fever and Bellii groups. In this study, we provided a global evolutionary genomic view of the intracellular Rickettsia that may help our understanding of their diversity, adaptation and fitness.
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