ArticleJournal of nanobiotechnology2022
Tailoring conductive inverse opal films with anisotropic elliptical porous patterns for nerve cell orientation.
Article in Journal of nanobiotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Advances in biomaterial-based tissue engineering for peripheral nerve injury repair.Bioactive materials · 2025Review
- Glucose oxidase: An emerging multidimensional treatment option for diabetic wound healing.Bioactive materials · 2025Review
- Biomimetic design and integrated biofabrication of an in-vitro three-dimensional multi-scale multilayer cortical model.Materials today. Bio · 2024Article
- Structural Color Colloidal Photonic Crystals for Biomedical Applications.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Recent advances in enhances peripheral nerve orientation: the synergy of micro or nano patterns with therapeutic tactics.Journal of nanobiotechnology · 2024Review
- Melanin-Integrated Structural Color Hybrid Hydrogels for Wound Healing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Bee Sting-Inspired Inflammation-Responsive Microneedles for Periodontal Disease Treatment.Research (Washington, D.C.) · 2023Article
- Recent Advances in Macroporous Hydrogels for Cell Behavior and Tissue Engineering.Gels (Basel, Switzerland) · 2022Review
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Authors and funding
7 authors.
Funding
Abstract
backgroundThe nervous system is critical to the operation of various organs and systems, while novel methods with designable neural induction remain to exploit.
resultsHere, we present a conductive inverse opal film with anisotropic elliptical porous patterns for nerve orientation induction. The films are fabricated based on polystyrene (PS) inverse opal scaffolds with periodical elliptical porous structure and poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) mixed polyacrylamide (PAAm) polymers fillers. It is demonstrated that the anisotropic elliptical surface topography allows the nerve cells to be induced into orientation connected with the stretching direction. Because of the anisotropic features of the film which can be stretched into different directions, nerve cells can be induced to grow in one or two directions, forming a neural network and promoting the connection of nerve cells. It is worth mentioning that the PEDOT:PSS-doped PAAm hydrogels endow the film with conductive properties, which makes the composite films be a suitable candidate for neurites growth and differentiation.
conclusionsAll these features of the conductive and anisotropic inverse opal films imply their great prospects in biomedical applications.
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