Evidence map›Paper›PMID 35264148›Full record

ArticleBMC pregnancy and childbirth2022

Clinical consequences of gestational diabetes mellitus and maternal obesity as defined by asian BMI thresholds in Viet Nam: a prospective, hospital-based, cohort study.

Serena Yue, Vu Thai Kim Thi, Le Phuong Dung, Bui Thi Hong Nhu, Evelyne Kestelyn, Dang Trong Thuan, Le Quang Thanh, Jane E Hirst

Open access · goldAbstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Serena YueNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK.
Vu Thai Kim ThiThe Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Viet Nam.
Le Phuong DungTu Du Hospital, Ho Chi Minh City, Viet Nam.
Bui Thi Hong NhuTu Du Hospital, Ho Chi Minh City, Viet Nam.
Evelyne KestelynThe Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Viet Nam.
Dang Trong ThuanThe Oxford University Clinical Research Unit (OUCRU), Ho Chi Minh City, Viet Nam.
Le Quang ThanhTu Du Hospital, Ho Chi Minh City, Viet Nam.
Jane E HirstNuffield Department of Women's & Reproductive Health, University of Oxford, Oxford, UK. jane.hirst@wrh.ox.ac.uk.
Oxford University Clinical Research Unit · VNViet Duc Hospital · VNGeorge Institute for Global Health · GBUniversity of Oxford · GB

Funding

Medical Research Council MR/T040750/1
6 · The paper itself

Abstract

backgroundGestational Diabetes Mellitus (GDM) is common in South East Asia, occurring at relatively lean Body Mass Index (BMI). Outside pregnancy, cardiometabolic risks increase at lower BMI in Asian populations, justifying Asian-specific thresholds for overweight and obesity. We aimed to explore the effects of GDM and obesity on perinatal outcomes using a WHO expert consultation-recommended Asian-specific definition of obesity.

methodsThis is a secondary analysis of a prospective, hospital-based, cohort study in Ho Chi Minh City. Participants were recruited from antenatal clinics between 19

resultsAmong 4,970 participants, 908 (18%) developed GDM. Compared to women without GDM, GDM increased risks for preterm birth (OR: 1.40, 95% CI: 1.09-1.78), higher birthweight (birthweight z-score 0.16 versus 0.09, p = 0.027), and LGA (OR 1.14, 0.89-1.46). GDM without obesity was associated with an increased risk of preterm birth (OR 1.35, 1.04-1.74). Obese women without GDM were more likely to deliver by caesarean section and have an LGA baby (1.80, 1.33-2.44 and 2.75, 1.88-4.03). The highest risks were observed amongst women with both GDM and obesity: caesarean Sect. (2.43, 1.49-3.96), LGA (3.36, 1.94-5.80) and preterm birth (2.42, 1.32-4.44).

conclusionsGDM was associated with an increased risk of preterm birth and larger newborn size. Using an Asian-specific definition of obesity, we demonstrate obese women with GDM are at the highest risk of adverse outcomes. Using a BMI threshold in pregnancy of 27.5 kg/m

Indexed as

Body Mass IndexAdultAsian PeopleBirth WeightCesarean SectionCohort StudiesDiabetes, GestationalFemaleHumansInfant, NewbornPregnancyPregnancy in ObesityPregnancy OutcomePremature BirthProspective StudiesVietnamAsian BMI thresholdGestational diabetes mellitusLarge for gestational ageMaternal obesityPerinatal outcomesPreterm birthPrimary C-sectionSouth East Asian

Identifiers

PMID35264148
PMCPMC8908699
OpenAlexW4220865938

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.