ArticleBMC neurology2022
Intrasellar pressure in patients with pituitary adenoma - relation to tumour size and growth pattern.
Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Regression of pituitary macroadenoma after endovascular embolization of thoracic cerebrospinal fluid-venous fistula for symptomatic intracranial hypotension: Illustrative case.Surgical neurology international · 2026Article
- Risk factors and prognosis of visual and cranial nerve deficits in patients operated for pituitary tumor - with a focus on intrasellar pressure.Acta neurochirurgica · 2025Article
- Complications following endoscopic transsphenoidal surgery for pituitary adenoma-special focus on intrasellar pressure.Acta neurochirurgica · 2025Observational
- Correlation between intrasellar pressure, pituitary adenoma invasiveness, pituitary dysfunction, and apoplexy.Frontiers in endocrinology · 2025Article
- Signal Transducer and Activator of Transcription 4 (STAT4) Association with Pituitary Adenoma.Medicina (Kaunas, Lithuania) · 2024Article
- Headache in patients with non-functioning pituitary adenoma before and after transsphenoidal surgery - a prospective study.Pituitary · 2024Article
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4 authors.
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Abstract
backgroundOnly a few earlier publications on intrasellar pressure (ISP) have not been able to fully clarify any association between ISP and pituitary adenoma size and growth pattern. The aim of the study was to determine if intrasellar pressure (ISP) is elevated in patients with pituitary adenoma, and if the pressure is associated with tumour size and growth pattern.
methodsThe study included 100 patients operated for suspected pituitary adenoma, who have had their ISP measured intraoperatively. All adenomas were classified on the basis of Knosp and SIPAP, from which further classification of invasiveness was performed. MRT examinations were used to calculate the tumour volume and diameter in three axes.
resultsAfter exclusions, 93 cases were analysed. The mean ISP was 23.0 ± 8.4 mmHg. There were positive correlations between ISP and tumour volume and tumour diameters along all three axes. Coronal tumour diameter showed the strongest correlation with ISP elevation in a multivariate effect test. Adenomas classified as parasellar invasive (Knosp grade 3-4) showed higher mean ISP than adenomas considered as non-invasive (Knosp 0-2).
conclusionsISP is affected by tumour anatomy and correlates positively with tumour volume. Tumour width, i.e. diameter in the coronal plane, appears to be the measure that most strongly affects the ISP. This is confirmed by the association between ISP elevation and parasellar growth.
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