ArticleEmerging microbes & infections2022
SARS-CoV-2 reinfection and COVID-19 severity.
Article in Emerging microbes & infections, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
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Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Risk Factors Contributing to Reinfection by SARS-CoV-2: A Systematic Review.Advances in respiratory medicine · 2023Pooled it
- Incidence and outcome of SARS-CoV-2 reinfection in the pre-Omicron era: A global systematic review and meta-analysis.Journal of global health · 2023Pooled it
- SARS-CoV-2 Reinfection and Severity of the Disease: A Systematic Review and Meta-Analysis.Viruses · 2023Pooled it
- Review
- Does asthma treatment influence COVID-19 severity? A comparative cohort study of SMART vs. Traditional therapy.European clinical respiratory journal · 2026Article
- The Role of Health-Related Factors in the Prevalence and Severity of COVID-19: A Retrospective Cohort Study Based on Sabzevar Persian Cohort Data.Health science reports · 2026Article
- Characteristic Symptoms and Associated Risk Factors of COVID-19 Reinfection in the Indonesian Community.Yonago acta medica · 2025Article
- Clinical and immunological insights into SARS-CoV-2 reinfection: a propensity score-matched cohort study.BMC infectious diseases · 2025Article
- Epidemiological features and risk factors of SARS-CoV-2 reinfection: a retrospective cohort analysis in Xiamen, China.Journal of thoracic disease · 2025Article
- SIRI+Q model with a limited capacity of isolation.Theory in biosciences = Theorie in den Biowissenschaften · 2025Article
- Detection of SARS-CoV-2 Reinfections Using Nucleocapsid Antibody Boosting.Emerging infectious diseases · 2025Article
- Predictors for Anxiety and Stress in Long COVID: A Study in the Brazilian Population.International journal of environmental research and public health · 2025Article
- Difference of clinical characteristics in patients with reinfection and primary infection variants of SARS-CoV-2: a retrospective study in China.BMC infectious diseases · 2025Article
- Analysis of COVID-19 reinfection and its influencing factors among primary healthcare workers in Jiangsu Province: a study based on the omicron variant epidemic.Frontiers in public health · 2025Article
- Compassionate Release and COVID-19: Analyzing Inconsistent Applications of the First Step Act by Federal Courts.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2025Article
- Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice.Nature communications · 2024Article
- A mathematical model for the within-host (re)infection dynamics of SARS-CoV-2.Mathematical biosciences · 2024Article
- The symptoms and interval of Omicron SARS-CoV-2 reinfection among healthcare workers in a hospital of Southern China: a cross-sectional study.BMC infectious diseases · 2024Article
- What Influence Could the Acceptance of Visitors Cause on the Epidemic Dynamics of a Reinfectious Disease?: A Mathematical Model.Acta biotheoretica · 2024Article
- SARS-CoV-2 reinfection with Omicron variant in Shaanxi Province, China: December 2022 to February 2023.BMC public health · 2024Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SARS-CoV-2 reinfection rate is low. The relative severity of the first and second episodes of infection remains poorly studied. In this study, we aimed at assessing the frequency of SARS-CoV-2 reinfections and comparing the severity of the first and second episodes of infection. We retrospectively included patients with SARS-CoV-2 positive RT-PCR at least 90 days after clinical recovery from a COVID-19 episode and with at least one negative RT-PCR after the first infection. Whole genome sequencing and variant-specific RT-PCR were performed and clinical symptoms and severity of infection were retrospectively documented from medical files. A total of 209 COVID-19 reinfected patients were identified, accounting for 0.4% of positive cases diagnosed from 19 March 2020 to 24 August 2021. Serology was performed in 64 patients, of whom 39 (60.1%) had antibodies against SARS-CoV-2 when sampled at the early stage of their second infection. Only seven patients (3.4%) were infected twice with the same variant. We observed no differences in clinical presentation, hospitalization rate, and transfer to ICU when comparing the two episodes of infections. Our results suggest that the severity of the second episode of COVID-19 is in the same range as that of the first infection, including patients with antibodies.
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