Evidence map›Paper›PMID 35264058›Full record

ArticleBioengineered2022

Knockdown of circ_0001679 alleviates lipopolysaccharide-induced MLE-12 lung cell injury by regulating the miR-338-3p/ mitogen-activated protein kinase 1 axis.

Shenggui Lu, Xinmiao Wu, Shuai Xin, Jing Zhang, Hanying Lin, Yu Miao, Yixin Li

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Functional roles of circular RNAs in lung injury.Frontiers in pharmacology · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shenggui LuIntensive Care Unit, The 910th Hospital of People's Liberation Army Joint Logistic Support Force, Quanzhou, China.
Xinmiao WuDepartment of Emergency, Hospital of Traditional Chinese Medicine, Quanzhou, Fujian Provice, China.
Shuai XinDepartment of Anesthesiology, The 910th Hospital of People's Liberation Army Joint Logistic Support Force, China.
Jing ZhangIntensive Care Unit, The 910th Hospital of People's Liberation Army Joint Logistic Support Force, Quanzhou, China.
Hanying LinIntensive Care Unit, The 910th Hospital of People's Liberation Army Joint Logistic Support Force, Quanzhou, China.
Yu MiaoDepartment of Nursing, The 910th Hospital of People's Liberation Army Joint Logistic Support Force, Quanzhou, Fujian, China.
Yixin LiIntensive Care Unit, The 910th Hospital of People's Liberation Army Joint Logistic Support Force, Quanzhou, China.ORCID 0000-0002-7697-8182
117th Hospital of People's Liberation Army · CNFujian University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The upregulation of circ_0001679 was reported in lipopolysaccharide (LPS)-induced lung injury mouse model, but its functional roles and mechanisms in LPS-induced lung injury remain to be investigated. In this study, we aimed to explore the potential role of circ_0001679 in septic acute lung injury. We initially established an

Indexed as

Acute Lung InjuryMicroRNAsAnimalsCaspase 3Interleukin-6LipopolysaccharidesLungMiceMitogen-Activated Protein Kinase 1RNA, CircularTumor Necrosis Factor-alphaCaspase 3Interleukin-6LipopolysaccharidesMicroRNAsMitogen-Activated Protein Kinase 1RNA, CircularTumor Necrosis Factor-alphacirc_0001679MAPK1miR-338-3pSeptic acute lung injury

Identifiers

PMID35264058
PMCPMC8973724
OpenAlexW4220758020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.