Evidence map›Paper›PMID 35263776›Full record

ArticleEuropean journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie2022

Childhood-Onset Myasthenia Gravis Patients Benefited from Thymectomy in a Long-Term Follow-up Observation.

Qing Zhang, Yayun Cao, Zhuajin Bi, Xue Ma, Mengge Yang, Huajie Gao, Mengcui Gui, Bitao Bu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qing ZhangDepartment of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.ORCID 0000-0002-5094-2747
Yayun CaoDepartment of Radiology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei Province, China.
Zhuajin BiDepartment of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Xue MaDepartment of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Mengge YangDepartment of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Huajie GaoDepartment of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Mengcui GuiDepartment of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Bitao BuDepartment of Neurology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe effect of thymectomy on the treatment of childhood-onset myasthenia gravis (CMG) remains debatable. The objective of this study was to evaluate the clinical outcome and relevant prognostic factors of thymectomy for CMG patients. MATERIALS AND

methodsA total of 32 CMG patients who underwent thymectomy before 18 years of age were included in this retrospective study. Clinical state following thymectomy was assessed by quantified myasthenia gravis (QMG) scores, myasthenia gravis-related activities of daily living (MG-ADL) scores, and Myasthenia Gravis Foundation of America postintervention status. Repeated-measures analysis of variance (ANOVA) examined the changes in postoperative scores during the 5-year follow-up. Univariate logistic regression was applied to identify factors associated with short-term (1-year postoperation) and long-term (5-year postoperation) clinical outcomes.

resultsRepeated-measures ANOVA showed that QMG scores (

conclusionOur results suggest that thymectomy is effective in treating CMG. Thymectomy could be recommended for CMG patients, especially for patients in the early course of GMG.

Indexed as

Myasthenia GravisThymectomyActivities of Daily LivingFollow-Up StudiesHumansRetrospective StudiesTreatment Outcome

Identifiers

PMID35263776
PMCPMC9666056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.