Evidence map›Paper›PMID 35263247›Full record

ArticleeLife2022

First-order visual interneurons distribute distinct contrast and luminance information across ON and OFF pathways to achieve stable behavior.

Madhura D Ketkar, Burak Gür, Sebastian Molina-Obando, Maria Ioannidou, Carlotta Martelli, Marion Silies

Abstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Imprecision in Vision: Lessons From Neural Circuits in the Fly.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026
    Review
  3. Afterimages drive a shared visual motion-reversal illusion inbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. A recurrent neural circuit inbioRxiv : the preprint server for biology · 2024
    Article
  11. Neuronal "parts list" and wiring diagram for a visual system.bioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Madhura D Ketkar *Institute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0002-0465-5616
Burak Gür *Institute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0001-8221-9767
Sebastian Molina-Obando *Institute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0003-1222-723X
Maria IoannidouInstitute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0003-2869-5468
Carlotta MartelliInstitute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0002-5663-6580
Marion SiliesInstitute of Developmental Biology and Neurobiology, Johannes-Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0003-2810-9828

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accurate processing of contrast is the basis for all visually guided behaviors. Visual scenes with rapidly changing illumination challenge contrast computation because photoreceptor adaptation is not fast enough to compensate for such changes. Yet, human perception of contrast is stable even when the visual environment is quickly changing, suggesting rapid post receptor luminance gain control. Similarly, in the fruit fly

Indexed as

Motion PerceptionVision, OcularAnimalsContrast SensitivityDrosophilaInterneuronsMotionPhotic StimulationVisual Pathwaysbehaviorcircuit organizationD. melanogasterluminance gainluminance invarianceneuroscienceON and OFF pathwaysvision

Identifiers

PMID35263247
PMCPMC8967382

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.