Evidence map›Paper›PMID 35263202›Full record

ArticleBioengineered2022

Notoginsenoside R1 relieves the myocardial infarction via activating the JAK2/STAT3 signaling pathway in vivo and in vitro.

Hai Xu, Xiwen Zhang, Yafei Shi, Kun Yu, Yicheng Jiang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hai XuDepartment of Cardiology, The First Afliated Hospital of Nanjing Medical University, Huaian City, Jiangsu Province, China.
Xiwen ZhangDepartment of Cardiology, The First Afliated Hospital of Nanjing Medical University, Huaian City, Jiangsu Province, China.
Yafei ShiDepartment of Cardiology, The First Afliated Hospital of Nanjing Medical University, Huaian City, Jiangsu Province, China.
Kun YuDepartment of Cardiology, The First Afliated Hospital of Nanjing Medical University, Huaian City, Jiangsu Province, China.
Yicheng JiangDepartment of Cardiology, The First Afliated Hospital of Nanjing Medical University, Huaian City, Jiangsu Province, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI), caused by continuous ischemia and hypoxia of the coronary artery, is one of the major causes of human mortality. This study aimed to investigate the role of notoginsenoside R1 (NGR1) in MI therapy.

Indexed as

Myocardial InfarctionSTAT3 Transcription FactorAnimalsApoptosisGinsenosidesHypoxiaJanus Kinase 2Nogo Receptor 1RatsSignal TransductionGinsenosidesJak2 protein, ratJanus Kinase 2Nogo Receptor 1notoginsenoside R1Rtn4r protein, ratSTAT3 Transcription Factorhypoxia/reoxygenationJAK2/STAT3Myocardial infarctionnotoginsenoside R1

Identifiers

PMID35263202
PMCPMC8974102
OpenAlexW4220686459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.