Evidence map›Paper›PMID 35263027›Full record

ArticleJournal of applied clinical medical physics2022

Deep learning-based auto segmentation using generative adversarial network on magnetic resonance images obtained for head and neck cancer patients.

Daisuke Kawahara, Masato Tsuneda, Shuichi Ozawa, Hiroyuki Okamoto, Mitsuhiro Nakamura, Teiji Nishio, Yasushi Nagata

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

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  4. Multi-modality brain tumor segmentation using dual-attention generative adversarial network.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Daisuke KawaharaDepartment of Radiation Oncology, Graduate School of Biomedical Health Sciences, Hiroshima University, Hiroshima, Japan.
Masato TsunedaDepartment of Radiation Oncology, MR Linac ART Division, Graduate School of Medicine, Chiba University, Chiba, Japan.
Shuichi OzawaHiroshima High-Precision Radiotherapy Cancer Center, Hiroshima, Japan.
Hiroyuki OkamotoDepartment of Medical Physics, National Cancer Center Hospital, Tokyo, Japan.
Mitsuhiro NakamuraDivision of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Teiji NishioMedical Physics Laboratory, Division of Health Science, Graduate School of Medicine, Osaka University, Osaka, Japan.
Yasushi NagataDepartment of Radiation Oncology, Graduate School of Biomedical Health Sciences, Hiroshima University, Hiroshima, Japan.
Hiroshima University · JPChiba University · JPKyoto University · JPOsaka Health Science University · JPTokyo National Hospital · JP

Funding

National Cancer Center Research and Development Fund 2020-J-3
6 · The paper itself

Abstract

purposeAdaptive radiotherapy requires auto-segmentation in patients with head and neck (HN) cancer. In the current study, we propose an auto-segmentation model using a generative adversarial network (GAN) on magnetic resonance (MR) images of HN cancer for MR-guided radiotherapy (MRgRT). MATERIAL AND

methodsIn the current study, we used a dataset from the American Association of Physicists in Medicine MRI Auto-Contouring (RT-MAC) Grand Challenge 2019. Specifically, eight structures in the MR images of HN region, namely submandibular glands, lymph node level II and level III, and parotid glands, were segmented with the deep learning models using a GAN and a fully convolutional network with a U-net. These images were compared with the clinically used atlas-based segmentation.

resultsThe mean Dice similarity coefficient (DSC) of the U-net and GAN models was significantly higher than that of the atlas-based method for all the structures (p < 0.05). Specifically, the maximum Hausdorff distance (HD) was significantly lower than that in the atlas method (p < 0.05). Comparing the 2.5D and 3D U-nets, the 3D U-net was superior in segmenting the organs at risk (OAR) for HN patients. The DSC was highest for 0.75-0.85, and the HD was lowest within 5.4 mm of the 2.5D GAN model in all the OARs.

conclusionsIn the current study, we investigated the auto-segmentation of the OAR for HN patients using U-net and GAN models on MR images. Our proposed model is potentially valuable for improving the efficiency of HN RT treatment planning.

Indexed as

Deep LearningHead and Neck NeoplasmsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingOrgans at RiskCNNdeep learningGANsegmentation

Identifiers

PMID35263027
PMCPMC9121028
OpenAlexW4221110016

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.