Evidence map›Paper›PMID 35263018›Full record

ArticleJournal of clinical laboratory analysis2022

Evaluation of a cardiac troponin process flow at the chest pain center with the shortest turnaround time.

Hao Wang, Xinyue Wang, Kouqiong Wang, Xincen Duan, Wenhai Jiang, Bin Tang, Baishen Pan, Beili Wang, Wei Guo

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hao WangDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-6881-9977
Xinyue WangDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Kouqiong WangDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Xincen DuanDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Wenhai JiangIT Center, Zhongshan Hospital, Fudan University, Shanghai, China.
Bin TangDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Baishen PanDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Beili WangDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-5167-170X
Wei GuoDepartment of Laboratory Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-4406-1094
Sun Yat-sen University · CNFudan University · CN

Funding

Constructing Project of Clinical Key Disciplines in Shanghai SHSLCZDZK03302Key Medical and Health Projects of Xiamen YDZX20193502000002National Natural Science Foundation of China 81772263National Natural Science Foundation of China 81902139National Natural Science Foundation of China 81972000National Natural Science Foundation of China 82000275Project funded by China Postdoctoral Science Foundation 2019M651370Scientific Research Fund by Zhongshan Hospital 418Shanghai Medical Key Specialty ZK2019B28Shanghai Post-doctoral Excellence Program 2018166Specialized Fund for the Clinical Researches of Zhongshan Hospital affiliated Fudan University 2018ZSLC05Specialized Fund for the Clinical Researches of Zhongshan Hospital affiliated Fudan University 2020ZSLC54
6 · The paper itself

Abstract

backgroundEarly diagnosis of myocardial infarction is crucial in chest pain management and cardiac troponin (cTn) test is an important step in it. Process improvement to shorten the test turnaround time (TAT) may improve patients' outcomes. The cTn test at chest pain center (CPC) of Zhongshan Hospital had the shortest TAT ever reported, but its process flow was not fully evaluated.

methodsWe performed a stepwise evaluation of CPC cTn TAT and explored the potential factor that might cause delay. The performance of CPC cTn test was also compared with cTn test and human chorionic gonadotropin (HCG) test ordered from emergency department (ED).

resultsAt least 95% of CPC cTn tests were completed in 60 min, while 62% in 30 min. The medians of monthly order-to-collect time, collect-to-received time, and received-to-result time were ~7 min, ~3 min, and ~13 min, respectively. The samples collected at the bedside had longer collect-to-received time than the ones collected at the blood draw site next to the laboratory. Compared to ED cTn test and ED HCG test, CPC cTn test took less time in each step. A combination of the sample type switch and the centrifugation time reduction contributed the most to the shortening of TAT, which was reflected in the received-to-result time.

conclusionsThe current process flow of CPC cTn test satisfied the requirements of chest pain management, giving an example of how to implement process improvement for emergency medicine to shorten TAT of laboratory tests.

Indexed as

Myocardial InfarctionTroponinBiomarkersChest PainEmergency Service, HospitalHumansPain ClinicsBiomarkersTroponincardiac troponinemergency medicinemyocardial infarctionprocess improvementturnaround time

Identifiers

PMID35263018
PMCPMC8993626
OpenAlexW4220999889

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.