ArticleThe Plant cell2022
BLISTER promotes seed maturation and fatty acid biosynthesis by interacting with WRINKLED1 to regulate chromatin dynamics in Arabidopsis.
Article in The Plant cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 34 citations in OpenAlex.
- From wrinkled seeds to plant oil accumulation networks: the legacy of a Plant Physiology classic.Plant physiology · 2026Review
- Lipid metabolism-driven regulatory networks involved in cone senescence and seed maturation in pine (Pinus massoniana).Communications biology · 2026Article
- SUMO-specific proteases SPF1 and SPF2 negatively regulate seed oil synthesis by mediating WRI1 deSUMOylation.Plant communications · 2026Article
- Article
- A comprehensive evaluation of metabolically engineered Cynara cardunculus calli as platform for valuable fatty acid derivatives production.Scientific reports · 2025Article
- Plant-specific BLISTER modulates miRNA biogenesis by regulating MIR transcription, HYL1 phosphorylation, and nuclear transport in Arabidopsis.Nucleic acids research · 2025Article
- Plant oil biosynthesis and genetic improvement: progress, challenges, and opportunities.Plant physiology · 2025Review
- Comparison of lipid profiles and nutritional quality of 11 red-flowered oil-tea camellia through quantitative lipidomics and chemometrics.Food chemistry: X · 2025Article
- SIZ1 SUMOylates and stabilizes WRI1 to safeguard seed filling and fatty acid biosynthesis under high-temperature stress.The Plant cell · 2025Article
- Circular RNAs derived from MIR156D promote rice heading by repressing transcription elongation of pri-miR156d through R-loop formation.Nature plants · 2025Article
- Article
- DEFGermplasm: a comprehensive digital platform for forest genomic and phenotype data integration.Forestry research · 2025Article
- Comparative lipidomics analysis reveals changes in lipid profile of Arabica coffee at different maturity.Food chemistry: X · 2024Article
- Dissecting the temporal genetic networks programming soybean embryo development from embryonic morphogenesis to post-germination.Plant cell reports · 2024Article
- High-Density Genetic Map Construction and Quantitative Trait Locus Analysis of Fruit- and Oil-Related Traits inInternational journal of molecular sciences · 2024Article
- The Genome of the Korean Island-OriginatedGenes · 2023Article
- A plant-unique protein BLISTER coordinates with core retromer to modulate endosomal sorting of plasma membrane and vacuolar proteins.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- A WRINKLE in the time of seed maturation: chromatin-level control of fatty acid biosynthesis.The Plant cell · 2022Article
- Overexpression of WRINKLED1 improves the weight and oil content in seeds of flax (Frontiers in plant science · 2022Article
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Authors and funding
15 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
WRINKLED1 (WRI1) is an important transcription factor that regulates seed oil biosynthesis. However, how WRI1 regulates gene expression during this process remains poorly understood. Here, we found that BLISTER (BLI) is expressed in maturing Arabidopsis thaliana seeds and acts as an interacting partner of WRI1. bli mutant seeds showed delayed maturation, a wrinkled seed phenotype, and reduced oil content, similar to the phenotypes of wri1. In contrast, BLI overexpression resulted in enlarged seeds and increased oil content. Gene expression and genetic analyses revealed that BLI plays a role in promoting the expression of WRI1 targets involved in fatty acid biosynthesis and regulates seed maturation together with WRI1. BLI is recruited by WRI1 to the AW boxes in the promoters of fatty acid biosynthesis genes. BLI shows a mutually exclusive interaction with the Polycomb-group protein CURLY LEAF (CLF) or the chromatin remodeling factor SWITCH/SUCROSE NONFERMENTING 3B (SWI3B), which facilitates gene expression by modifying nucleosomal occupancy and histone modifications. Together, these data suggest that BLI promotes the expression of fatty acid biosynthesis genes by interacting with WRI1 to regulate chromatin dynamics, leading to increased fatty acid production. These findings provide insights into the roles of the WRI1-BLI-CLF-SWI3B module in mediating seed maturation and gene expression.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.