Evidence map›Paper›PMID 35262411›Full record

ArticleMicrobiology spectrum2022

Molecular Diagnosis of Cat Scratch Disease: a 25-Year Retrospective Comparative Analysis of Various Clinical Specimens and Different PCR Assays.

Sher Goaz, Michal Rasis, Inbal Binsky Ehrenreich, Lev Shapira, Ora Halutz, Merav Graidy-Varon, Cecilia Leibovitch, Noam Maisler, Daniel Glikman, Moshe Ephros and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Clinical and epidemiological features of cat-scratch disease: a 16-year case retrospective study in a portuguese tertiary care centre.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Tropical medicine and infectious disease · 2024
    Article
  9. Review
  10. Limitations of Serological Diagnosis of Typical Cat Scratch Disease and Recommendations for the Diagnostic Procedure.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sher GoazThe Bernard Pridan Laboratory for Molecular Biology of Infectious diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Michal RasisThe Bernard Pridan Laboratory for Molecular Biology of Infectious diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Inbal Binsky EhrenreichDYN Diagnostics, Migdal HaEmeq, Israel.
Lev ShapiraThe Bernard Pridan Laboratory for Molecular Biology of Infectious diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Ora HalutzMicrobiology Laboratory, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Merav Graidy-VaronMicrobiology Laboratory, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Cecilia LeibovitchMicrobiology Laboratory, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Noam MaislerDYN Diagnostics, Migdal HaEmeq, Israel.
Daniel GlikmanThe Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel.
Moshe EphrosPediatric Infectious Disease Unit, Carmel Medical Center and the Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Michael GiladiThe Bernard Pridan Laboratory for Molecular Biology of Infectious diseases, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.ORCID 0000-0002-5449-8655
Tel Aviv Sourasky Medical Center · ILBar-Ilan University · ILTechnion – Israel Institute of Technology · ILTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cat-scratch disease (CSD), caused primarily by Bartonella henselae, is a common etiology of infectious regional lymphadenopathy. Lymphadenopathy is preceded by a primary inoculation lesion and may progress to suppuration. Laboratory diagnosis of CSD is hampered by the limitations of available confirmatory tests. PCR, in general, is highly sensitive and specific; however, clinical sensitivity in CSD varies greatly between studies. We aimed to identify clinical specimens and PCR assays best suited for CSD diagnosis using a national CSD registry and a uniform case definition. Different clinical specimens and PCR assays, including conventional and real-time PCR, were evaluated. PCR was positive in 335/390 (86%) CSD patients and 425/482 (88%) PCR tests. The highest PCR sensitivity was achieved in lymph node pus aspirates (96%;

Indexed as

Bartonella henselaeCat-Scratch DiseaseLymphadenopathyDNA, BacterialHumansLymph NodesReal-Time Polymerase Chain ReactionRetrospective StudiesSuppurationDNA, BacterialBartonella henselaecat scratch diseasemolecular diagnosisPCR

Identifiers

PMID35262411
PMCPMC9045166
OpenAlexW4220684701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.