Evidence map›Paper›PMID 35262378›Full record

ArticleJournal of virology2022

Short 5' Untranslated Region Enables Optimal Translation of Plant Virus Tricistronic RNA via Leaky Scanning.

Yuji Fujimoto, Takuya Keima, Masayoshi Hashimoto, Yuka Hagiwara-Komoda, Naoi Hosoe, Shuko Nishida, Takamichi Nijo, Kenro Oshima, Jeanmarie Verchot, Shigetou Namba and 1 more

Abstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Plants (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Leaky ribosomal scanning enables tunable translation of bicistronic ORFs in green algae.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuji FujimotoGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.
Takuya KeimaGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.
Masayoshi HashimotoGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.
Yuka Hagiwara-KomodaDepartment of Sustainable Agriculture, College of Agriculture, Food and Environment Sciences, Rakuno Gakuen University, Hokkaido, Japan.
Naoi HosoeGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.
Shuko NishidaGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.
Takamichi NijoGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.
Kenro OshimaFaculty of Bioscience, Hosei Universitygrid.257114.4, Tokyo, Japan.
Jeanmarie VerchotDepartment of Plant Pathology and Microbiology, Texas A&M University, College Station, Texas, USA.
Shigetou NambaGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.
Yasuyuki YamajiGraduate School of Agricultural and Life Sciences, The University of Tokyogrid.26999.3d, Tokyo, Japan.ORCID 0000-0002-8110-2900

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regardless of the general model of translation in eukaryotic cells, a number of studies suggested that many mRNAs encode multiple proteins. Leaky scanning, which supplies ribosomes to downstream open reading frames (ORFs) by readthrough of upstream ORFs, has great potential to translate polycistronic mRNAs. However, the mRNA elements controlling leaky scanning and their biological relevance have rarely been elucidated, with exceptions such as the Kozak sequence. Here, we have analyzed the strategy of a plant RNA virus to translate three movement proteins from a single RNA molecule through leaky scanning. The

Indexed as

Plant VirusesProtein BiosynthesisRNA Viruses5' Untranslated RegionsOpen Reading FramesRNA, MessengerRNA, Viral5' Untranslated RegionsRNA, MessengerRNA, Viralleaky scanningplant viruspotexvirustranslation initiationUTR

Identifiers

PMID35262378
PMCPMC9006964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.