Evidence map›Paper›PMID 35261959›Full record

ArticleCurrent developments in nutrition2022

Recruitment and Retention of Healthy, Postmenopausal Women of African and European Ancestry: Results from a Dietary Intervention with Repeated Biospecimen Collections.

Susan E McCann, Elisa M Rodriguez, Deborah Erwin, Song Yao, David Tritchler, Meredith A J Hullar, Tracey O'Connor, Johanna W Lampe

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01698294 (A Pilot Study of the Flaxseed Effects on Hormones and Lignans), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01698294 nacompletednot on this map

A Pilot Study of the Flaxseed Effects on Hormones and Lignans: Role of Race, Genes, and Gut Microbiome

TypeinterventionalSponsorRoswell Park Cancer InstituteRan2012 to 2017Enrolled258ConditionsNo Evidence of DiseaseArmsClinical Observation, Flaxseed, Laboratory Biomarker Analysis, Questionnaire Administration
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Susan E McCannDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID https://orcid.org/0000-0002-2079-8705
Elisa M RodriguezDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Deborah ErwinDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Song YaoDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID https://orcid.org/0000-0001-9442-1313
David TritchlerDepartment of Biostatistics, University at Buffalo, Buffalo, NY, USA.
Meredith A J HullarCancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Tracey O'ConnorDepartment of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Johanna W LampeCancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Roswell Park Comprehensive Cancer Center · USFred Hutch Cancer Center · USUniversity at Buffalo, State University of New York · US

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI CANDACE S JOHNSON · 1985 to 2026
$116.6M
Flaxseed effects on hormones and lignans: role of race, genes, and gut microbiomeU01CA161809 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI LAMPE, JOHANNA W, MCCANN, SUSAN E · 2012 to 2016
$4.3M
NCI NIH HHS P30 CA015704NCI NIH HHS P30 CA016056NCI NIH HHS U01 CA161809
6 · The paper itself

Abstract

Recruitment of minority participants to clinical trials, especially studies without therapeutic intent, has been historically challenging. This study describes barriers to and successes of recruitment and retention strategies to dietary studies. A flaxseed study was conducted in healthy, postmenopausal women of African ancestry (AA) and European ancestry (EA) to assess associations between gut microbial community composition and host metabolism (NCT01698294). To ensure equitable participation by AA and EA women, multiple forms of recruitment were utilized, including advertisements, posters, e-mail, word of mouth, and community outreach. Successful recruitment and retention of AA women to the intervention depended upon the specific methods used. AA women compared with EA women were more likely to respond to direct recruitment and community-based methods, rather than general advertisements. However, once women expressed interest, similar rates of consent were observed for AA and EA women (AA and EA: 51.6% vs. 55.7%, respectively;

Indexed as

African ancestrydietary interventionsEuropean ancestryrecruitmentretention

Identifiers

PMID35261959
PMCPMC8894291
OpenAlexW4210651622

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.