Evidence map›Paper›PMID 35261887›Full record

ArticleTranslational cancer research2022

Knockdown of

Luqun Tang, Lijun Wang, Tao Yu, Tongpeng Xu, Lizhen Zhang, Yongqian Shu

Open access · diamondAbstract read
In one paragraph

Article in Translational cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Luqun Tang *Department of Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lijun Wang *Department of Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Tao YuDepartment of Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Tongpeng XuDepartment of Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Lizhen ZhangDepartment of Radiation Oncology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yongqian ShuDepartment of Oncology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNNanjing Medical University · CNSecond Affiliated Hospital of Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To investigate the role and mechanism of erythropoietin-producing hepatocyte receptor B3 ( Methods: Results: Conclusions: EphB3 knockdown inhibited the proliferation of esophageal squamous cell cancer partly through the AKT signaling pathway and repressed cell migration and invasion via EMT reversion. The findings of the study suggested that EphB3 might be a novel target for the therapy of esophageal carcinoma.

Indexed as

epithelial-mesenchymal transition (EMT)Erythropoietin-producing hepatocyte receptor B3 (EphB3)esophageal squamous cell carcinoma (ESCC)proliferation of cells

Identifiers

PMID35261887
PMCPMC8841496
OpenAlexW4205552744

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.