Evidence map›Paper›PMID 35261809›Full record

ArticleAmerican journal of cancer research2022

A novel HDAC11 inhibitor potentiates the tumoricidal effects of cordycepin against malignant peripheral nerve sheath tumor through the Hippo signaling pathway.

Po-Yuan Huang, I-An Shih, Ying-Chih Liao, Huey-Ling You, Ming-Jen Lee

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Po-Yuan HuangDepartment of Neurology, National Taiwan University Hospital, National Taiwan University College of Medicine Taipei, Taiwan.
I-An ShihDepartment of Neurology, National Taiwan University Hospital, National Taiwan University College of Medicine Taipei, Taiwan.
Ying-Chih LiaoDepartment of Neurology, National Taiwan University Hospital, National Taiwan University College of Medicine Taipei, Taiwan.
Huey-Ling YouDepartment of Neurology, National Taiwan University Hospital, National Taiwan University College of Medicine Taipei, Taiwan.
Ming-Jen LeeDepartment of Neurology, National Taiwan University Hospital, National Taiwan University College of Medicine Taipei, Taiwan.
National Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disorder. Clinically, the hallmarks of NF1 include skin pigmentation and cutaneous neurofibroma. Some NF1 patients develop plexiform neurofibroma (PN) since early childhood. Pathologically, PN contains abundant Schwann cells, blood vessels and connective tissues, which may transform into a malignant peripheral nerve sheath tumor (MPNST). MPNST is a highly invasive sarcoma without any effective therapy. Recently, both

Indexed as

ChIP-qPCRcordycepinFT895HDAC11 inhibitorHippo pathwayMPNST

Identifiers

PMID35261809
PMCPMC8899988
OpenAlexW4226487037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.