Evidence map›Paper›PMID 35261648›Full record

ArticleAsian journal of pharmaceutical sciences2022

One-pot preparation of nanodispersion with readily available components for localized tumor photothermal and photodynamic therapy.

Anpu Yang, Yanan Sun, Bochen Lyu, Binlong Chen, Zhipu Fan, Minghui Li, Yao Zhao, Jijun Fu, Bing He, Hua Zhang and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Anpu YangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Yanan SunState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Bochen LyuState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Binlong ChenState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Zhipu FanState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Minghui LiState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Yao ZhaoState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Jijun FuSchool of Pharmaceutical Science, Guangzhou Medical University, Guangzhou 511436, China.
Bing HeState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Hua ZhangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Xueqing WangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Wenbing DaiState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Qiang ZhangState Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, xueyuan road 38, haidian district, Peking University, Beijing 100191, China.
Peking University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photothermal (PTT) and photodynamic (PDT) combined therapy has been hindered to clinical translation, due to the lack of available biomaterials, difficult designs of functions, and complex chemical synthetic or preparation procedures. To actualize a high-efficiency combination therapy for cancer via a feasible approach, three readily available materials are simply associated together in one-pot, namely the single-walled carbon nanohorns (SWCNH), zinc phthalocyanine (ZnPc), and surfactant TPGS. The established nanodispersion is recorded as PCT. The association of SWCNH/ZnPc/TPGS was confirmed by energy dispersive spectrum, Raman spectrum and thermogravimetric analysis. Under lighting, PCT induced a temperature rising up to about 60 °C due to the presence of SWCNH, production a 7-folds of singlet oxygen level elevation because of ZnPc, which destroyed almost all 4T1 tumor cells

Indexed as

Carbon nanohornPhotodynamic therapyPhotothermal therapyZinc phthalocyanine

Identifiers

PMID35261648
PMCPMC8888177
OpenAlexW3211165302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.