Evidence map›Paper›PMID 35261174›Full record

ArticleBasic & clinical pharmacology & toxicology2022

"Biosimilar, so it looks alike, but what does it mean?" A qualitative study of Danish patients' perceptions of biosimilars.

Meera Varma, Anna Birna Almarsdóttir, Louise C Druedahl

Open access · greenAbstract read
In one paragraph

Article in Basic & clinical pharmacology & toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Meera VarmaFaculty of Health and Medical Sciences, Department of Pharmacy, Social and Clinical Pharmacy Research Group, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-7013-9396
Anna Birna AlmarsdóttirFaculty of Health and Medical Sciences, Department of Pharmacy, Social and Clinical Pharmacy Research Group, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-5354-2976
Louise C DruedahlFaculty of Health and Medical Sciences, Department of Pharmacy, Social and Clinical Pharmacy Research Group, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-8979-8666
University of Copenhagen · DK

Funding

LEO Pharma A/SNovo Nordisk Foundation NNF17SA0027784
6 · The paper itself

Abstract

Biosimilars are highly similar follow-on products for biologics that can foster biologics competition. Questionnaire studies have attempted to gauge the patient perspective on biosimilars, but none have delved deeper into how patients view biologics and switching of these. Considering Denmark has one of the highest biosimilar uptakes worldwide, the aim of this study was to investigate how Danish patients with psoriasis, arthritic diseases or inflammatory bowel disease perceive biosimilars. Twelve participants were semi-structurally interviewed in either a focus group or an internet-based, individual interview between May 2019 and July 2019. Content analysis was inductively applied. Participants on originators voiced more reluctance towards using biosimilars than those already using them. Both participants using originator and biosimilar products expressed concerns about reoccurrence of disease symptoms due to differences in effectiveness and safety. Participants generally struggled with understanding biosimilarity, and they voiced a need to be well-informed about switching. They were all aware of and accepted how healthcare budget restrictions played a role in the push to use biosimilars. To improve biosimilar uptake and willingness to switch to a biosimilar, patient-centred information on efficacy and safety and explanation of the societal benefits of the savings from using biosimilars must be carefully communicated.

Indexed as

Biosimilar PharmaceuticalsInflammatory Bowel DiseasesPsoriasisDenmarkHumansSurveys and QuestionnairesBiosimilar Pharmaceuticalsbiologicsbiosimilarpatientperspectiveswitching

Identifiers

PMID35261174
PMCPMC9314148
OpenAlexW4220852316

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.