ArticleNature neuroscience2022
Neurons detect cognitive boundaries to structure episodic memories in humans.
Article in Nature neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Context-dependent abstraction of temporal relationships during naturalistic episodic memory.iScience · 2026Article
- Hierarchical learning creates invariant schema within plastic neural networks.Journal of computational neuroscience · 2026Article
- Human neuron activity during an 83-minute movie from 2,286 neurons and 29 patients.Scientific data · 2026Article
- Neural pattern stability within events is similar in young and older adults.Scientific reports · 2026Article
- Frontal cortex organization supporting audiovisual processing during naturalistic viewing.Nature communications · 2026Article
- Neural population dynamics and temporal context cells in macaque medial parietal cortex support temporal order memory.PLoS biology · 2026Article
- Article
- Controlled Semantic Cognition: Precision Recordings Converge With in Silico Experiments to Reveal the Inner Workings of the Anterior Temporal Lobe Hub.Neurobiology of language (Cambridge, Mass.) · 2026Review
- A Passage of Time Signal in the Human Brain.eNeuro · 2026Article
- Separating the details while maintaining the story: within event episodic integration and across event semantic contiguity in memory.Frontiers in psychology · 2026Article
- Hippocampal Drift Rate Reflects the Temporal Organization of Memories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Primate Hippocampus Constructs a Temporal Scaffold Anchored to Behavioral Events.bioRxiv : the preprint server for biology · 2025Article
- Neural Representation of Episodic Time.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Reduced temporal organization of narrative recall in adults with moderate-severe traumatic brain injury.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Motifs of human high-frequency oscillations structure processing and memory of continuous audiovisual narratives.Science advances · 2025Article
- Adding meaningful distal action effects in feature binding.Attention, perception & psychophysics · 2025Article
- Hippocampal systems for event encoding and sequencing during ongoing narrative comprehension.Communications biology · 2025Article
- Locus coeruleus activation 'resets' hippocampal event representations and separates adjacent memories.bioRxiv : the preprint server for biology · 2025Article
- Neural state changes during movie watching relate to episodic memory in younger and older adults.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- A Rapid Cortical Learning Process Supporting Students' Knowledge Construction During Real Classroom Teaching.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
While experience is continuous, memories are organized as discrete events. Cognitive boundaries are thought to segment experience and structure memory, but how this process is implemented remains unclear. We recorded the activity of single neurons in the human medial temporal lobe (MTL) during the formation and retrieval of memories with complex narratives. Here, we show that neurons responded to abstract cognitive boundaries between different episodes. Boundary-induced neural state changes during encoding predicted subsequent recognition accuracy but impaired event order memory, mirroring a fundamental behavioral tradeoff between content and time memory. Furthermore, the neural state following boundaries was reinstated during both successful retrieval and false memories. These findings reveal a neuronal substrate for detecting cognitive boundaries that transform experience into mnemonic episodes and structure mental time travel during retrieval.
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