ArticleScientific reports2022
Associations of maternal gestational hypertension with high blood pressure and overweight/obesity in their adolescent offspring: a retrospective cohort study.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Association of hypertensive disorders of pregnancy with offspring cardiometabolic indicators: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Multi-Organ Phenotypes of Offspring Born Following Hypertensive Disorders of Pregnancy: A Systematic Review.Journal of the American Heart Association · 2024Pooled it
- A Systematic Patent Review (2008-2023) for Treatment in Pregnancy.Current medicinal chemistry · 2024Pooled it
- Association of gestational hypertension and preeclampsia with offspring adiposity: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Trial
- Neonatal hyperoxia exposure does not exacerbate hypertension programmed by maternal obesity.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- Prenatal factors shaping adolescent cardiovascular function and cardiometabolic risk trajectories.Frontiers in pediatrics · 2026Review
- Maternal hypertension and telomere length are associated with weight for age Z score change from birth to 6 months of age in a predominantly Latinx cohort.BMC pregnancy and childbirth · 2025Article
- Exploring maternal health, lifestyle, and socioeconomic influences on childhood obesity in Australia.BMC public health · 2025Article
- The effect of Akkermansia in patients with pregnancy induced hypertension.BMC microbiology · 2025Article
- Maternal Cardiometabolic Risk Factors in Pregnancy and Offspring Blood Pressure at Age 2 to 18 Years.JAMA network open · 2025Article
- A Review of the Use of Data Analytics to Address Preeclampsia in Ecuador Between 2020 and 2024.Diagnostics (Basel, Switzerland) · 2025Review
- Obstetric and Neonatal Outcomes in Overweight Adolescent Pregnant Mothers.Journal of obstetrics and gynaecology of India · 2025Article
- Prevalence and factors associated with hypertension among children attending pre-schools in Dar es Salaam, Tanzania.Italian journal of pediatrics · 2025Article
- Article
- Environments affect blood pressure in toddlers: The Japan Environment and Children's Study.Pediatric research · 2024Article
- Maternal cardiovascular disorders before and during pregnancy and offspring cardiovascular risk across the life course.Nature reviews. Cardiology · 2023Review
- The Association between Gut Microbiome and Pregnancy-Induced Hypertension: A Nested Case-Control Study.Nutrients · 2022Article
- Interplay of Environmental, Individual and Genetic Factors in Rheumatoid Arthritis Provocation.International journal of molecular sciences · 2022Review
- Effectiveness of avocado leaf extract (F1000Research · 2022Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maternal hypertensive disorders during pregnancy may have an impact on fetal development and the health of the offspring in later life. The aim of the study was to evaluate the associations of maternal gestational hypertension (GH) with high blood pressure (HBP) (prehypertension/hypertension) and overweight/obesity in their adolescent offspring at the age of 12 to 15 years. We analyzed data of 4819 participants born in Kaunas city during 1995-1998 who were included in the study "Prevalence and Risk Factors of HBP in 12-15-Year-Old Lithuanian Children and Adolescents". The diagnosis of maternal gestational hypertension was obtained from medical records. Associations of maternal GH with their offspring's HBP and overweight/obesity in adolescence were assessed by multivariate logistic regression analysis. Among 4819 adolescents of 12-15 years of age, 25.7% had HBP, 12% had overweight, and 2.5% had obesity. Of 4819 mothers, 92.3% were normotensive during pregnancy, and 7.7% had GH. In the multivariate analysis after adjustment for age, sex, birth weight, adolescent BMI, and maternal pre/early pregnancy BMI, adolescent offspring born to mothers with GH had higher odds of prehypertension, hypertension, and prehypertension/hypertension (aOR 1.58; 95% CI 1.13-2.22; aOR 1.87; 95% CI 1.41-2.47; and aOR 1.76, 95% CI 1.39-2.24; respectively), compared to the offspring of normotensive mothers. After adjustment for age, sex, birth weight, and maternal pre/early pregnancy BMI, a significant association was found between maternal GH and the offspring's overweight/obesity in adolescence (aOR 1.41; 95% CI 1.04-1.91). The findings of this study suggest that maternal GH is associated with an increased odds of HBP (prehypertension and hypertension, both separately and combined) and overweight/obesity in their offspring during adolescence.
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