Evidence map›Paper›PMID 35260711›Full record

ArticleScientific reports2022

Exposure to 1800 MHz LTE electromagnetic fields under proinflammatory conditions decreases the response strength and increases the acoustic threshold of auditory cortical neurons.

Samira Souffi, Julie Lameth, Quentin Gaucher, Délia Arnaud-Cormos, Philippe Lévêque, Jean-Marc Edeline, Michel Mallat

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Samira Souffi *Paris Saclay Institute of Neuroscience, Neuro-PSI, UMR 9197 CNRS, Université Paris-Sud, 91405, Orsay Cedex, France.
Julie Lameth *Institut du Cerveau - Paris Brain Institute, ICM, Inserm, CNRS, Sorbonne Université, APHP, Hopital Pitie Salpetrières, 75013, Paris, France.
Quentin GaucherParis Saclay Institute of Neuroscience, Neuro-PSI, UMR 9197 CNRS, Université Paris-Sud, 91405, Orsay Cedex, France.
Délia Arnaud-CormosCNRS, XLIM, UMR 7252, Univ. Limoges, 123 avenue Albert Thomas, 87000, Limoges, France.
Philippe LévêqueCNRS, XLIM, UMR 7252, Univ. Limoges, 123 avenue Albert Thomas, 87000, Limoges, France.
Jean-Marc EdelineParis Saclay Institute of Neuroscience, Neuro-PSI, UMR 9197 CNRS, Université Paris-Sud, 91405, Orsay Cedex, France. jean-marc.edeline@u-psud.fr.
Michel MallatInstitut du Cerveau - Paris Brain Institute, ICM, Inserm, CNRS, Sorbonne Université, APHP, Hopital Pitie Salpetrières, 75013, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRCEA Paris-Saclay · FRCentre National de la Recherche Scientifique · FRInserm · FRInstitut des Neurosciences Paris-Saclay · FRInstitut Universitaire de France · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased needs for mobile phone communications have raised successive generations (G) of wireless technologies, which could differentially affect biological systems. To test this, we exposed rats to single head-only exposure of a 4G long-term evolution (LTE)-1800 MHz electromagnetic field (EMF) for 2 h. We then assessed the impact on microglial space coverage and electrophysiological neuronal activity in the primary auditory cortex (ACx), under acute neuroinflammation induced by lipopolysaccharide. The mean specific absorption rate in the ACx was 0.5 W/kg. Multiunit recording revealed that LTE-EMF triggered reduction in the response strength to pure tones and to natural vocalizations, together with an increase in acoustic threshold in the low and medium frequencies. Iba1 immunohistochemistry showed no change in the area covered by microglia cell bodies and processes. In healthy rats, the same LTE-exposure induced no change in response strength and acoustic threshold. Our data indicate that acute neuroinflammation sensitizes neuronal responses to LTE-EMF, which leads to an altered processing of acoustic stimuli in the ACx.

Indexed as

Auditory CortexCell PhoneAcousticsAnimalsElectromagnetic FieldsNeuronsRats

Identifiers

PMID35260711
PMCPMC8902282
OpenAlexW4220895468

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.