Evidence map›Paper›PMID 35260688›Full record

ArticleScientific reports2022

Discriminant analysis and binary logistic regression enable more accurate prediction of autism spectrum disorder than principal component analysis.

Wail M Hassan, Abeer Al-Dbass, Laila Al-Ayadhi, Ramesa Shafi Bhat, Afaf El-Ansary

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Wail M HassanDepartment of Biomedical Sciences, University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA.
Abeer Al-DbassBiochemistry Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Laila Al-AyadhiDepartment of Physiology, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ramesa Shafi BhatBiochemistry Department, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Afaf El-AnsaryAutism Research and Treatment Center, Riyadh, Saudi Arabia. afafkelansary@gmail.com.
King Saud University · SAUniversity of Missouri–Kansas City · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction and restricted, repetitive behavior. Multiple studies have suggested mitochondrial dysfunction, glutamate excitotoxicity, and impaired detoxification mechanism as accepted etiological mechanisms of ASD that can be targeted for therapeutic intervention. In the current study, blood samples were collected from 40 people with autism and 40 control participants after informed consent and full approval from the Institutional Review Board of King Saud University. Sodium (Na

Indexed as

Autism Spectrum DisorderDiscriminant AnalysisGlutathione TransferaseHumansL-Lactate DehydrogenaseLogistic ModelsPrincipal Component AnalysisSodiumGlutathione TransferaseL-Lactate DehydrogenaseSodium

Identifiers

PMID35260688
PMCPMC8904630
OpenAlexW4220995743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.