Evidence map›Paper›PMID 35260636›Full record

ArticleScientific reports2022

Comparison of depressive symptoms and inflammation between sexual minorities and heterosexuals using NHANES study of 8538 participants.

Amandeep Mann, Ava Chan, Atharva Rohatgi, Michelle Ann Caesar, Juno Obedin-Maliver, Daniel S Kapp

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Amandeep MannPalo Alto Medical Foundation Research Institute, 795 El Camino Real, Palo Alto, CA, 94301, USA. manna1@sutterhealth.org.
Ava ChanPalo Alto Medical Foundation Research Institute, 795 El Camino Real, Palo Alto, CA, 94301, USA.
Atharva RohatgiPalo Alto Medical Foundation Research Institute, 795 El Camino Real, Palo Alto, CA, 94301, USA.
Michelle Ann CaesarCalifornia Pacific Medical Center Research Institute, 475 Brannan St, San Francisco, CA, 94107, USA.
Juno Obedin-MaliverDepartment of Obstetrics and Gynecology, Stanford University School of Medicine, 900 Blake Wilbur Dr. Ste W0050, Stanford, CA, 94304, USA.
Daniel S KappDepartment of Radiation Oncology, Stanford University School of Medicine, 875 Blake Wilbur Dr, Stanford, CA, 94304, USA.
Palo Alto Institute · USStanford University · USCalifornia Pacific Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aims to compare the rate of depressive symptoms and inflammation levels between sexual minorities and heterosexuals. Data were obtained from the National Health and Nutrition Examination Survey from 2005 to 2010. Depressive-related symptoms were measured using the Patient Health Questionnaire-9 scoring system. C-reactive protein was analyzed with the Behring Nephelometer. Of 8538 participants, 95.8% self-reported as heterosexual and 4.2% as sexual minority. Depressive symptoms were reported in 7.1% of heterosexuals compared to 15.8% in sexual minorities (P = 0.001). In heterosexuals, C-reactive protein was higher in those with depressive symptoms compared to those without (P < 0.001). In sexual minorities, similar results were found, however, it was statistically insignificant. The intersection group of black sexual minority females reported the highest rate of depressive symptoms at 33.4%. We found that depressive symptoms were higher in sexual minorities compared to heterosexuals. Furthermore, systemic inflammation was highest in the intersection group of black sexual minority females.

Indexed as

HeterosexualitySexual and Gender MinoritiesC-Reactive ProteinDepressionFemaleHumansInflammationNutrition SurveysSexual BehaviorC-Reactive Protein

Identifiers

PMID35260636
PMCPMC8904501
OpenAlexW4220729378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.