Evidence map›Paper›PMID 35260476›Full record

ArticleRMD open2022

Eosinophilic granulomatosis with polyangiitis exhibits T cell activation and IgG4 immune response in the tissue; comparison with IgG4-related disease.

Satoshi Kubo, Ryuichiro Kanda, Aya Nawata, Yusuke Miyazaki, Akio Kawabe, Kentaro Hanami, Keisuke Nakatsuka, Kazuyoshi Saito, Shingo Nakayamada, Yoshiya Tanaka

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Pursuing Precision Medicine in Managing Rheumatoid Arthritis.International journal of rheumatic diseases · 2025
    Review
  4. Article
  5. Review
  6. IgG4-related disease for the hematologist.Hematology. American Society of Hematology. Education Program · 2024
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. [Immunoglobulin-G4-related disease].Zeitschrift fur Rheumatologie · 2022
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Satoshi KuboFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.ORCID 0000-0001-9693-9263
Ryuichiro KandaFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.
Aya NawataFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.
Yusuke MiyazakiFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.ORCID 0000-0001-5692-3881
Akio KawabeFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.
Kentaro HanamiDepartment of Rheumatology and Diabetology, Wakamatsu Hospital of the University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan.
Keisuke NakatsukaDepartment of Internal Medicine, Fukuoka Yutaka Central Hospital, Nogata, Fukuoka, Japan.
Kazuyoshi SaitoDepartment of Clinical Immunology and Rheumatology, Tobata General Hospital, Kitakyushu, Fukuoka, Japan.
Shingo NakayamadaFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.
Yoshiya TanakaFirst Department of Internal Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan tanaka@med.uoeh-u.ac.jp.ORCID 0000-0002-0807-7139
University of Occupational and Environmental Health Japan · JPFukuoka Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo study the pathophysiological differences of EGPA and IgG

methodsClinical and pathological findings were compared in patients with EGPA and IgG

resultsAn elevation of the IgG4 level was found in all EGPA cases, with the accompanying pathological findings of lymphocytic infiltration and fibrosis observed in 30.8% patients, and the elevation of IgG

conclusionsThe elevation of serum IgG

Indexed as

Churg-Strauss SyndromeGranulomatosis with PolyangiitisImmunoglobulin G4-Related DiseaseHumansImmunoglobulin GLeukocytes, MononuclearLymphocyte ActivationImmunoglobulin Gautoimmune diseasesgranulomatosis with polyangiitisinflammation

Identifiers

PMID35260476
PMCPMC8906049
OpenAlexW4220929664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.