Evidence map›Paper›PMID 35260396›Full record

ArticleBMJ case reports2022

COVID-19 encephalopathy: an unusual presentation with new-onset seizure causing convulsive status epilepticus.

Aisha Fareed Siddiqui, Sheema Saadia, Taymmia Ejaz, Zain Mushtaq

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Aisha Fareed SiddiquiSection of Internal Medicine, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan.ORCID http://orcid.org/0000-0003-1571-2820
Sheema SaadiaSection of Internal Medicine, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan.
Taymmia EjazSection of Internal Medicine, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan.
Zain MushtaqSection of Internal Medicine, Department of Medicine, The Aga Khan University Hospital, Karachi, Pakistan zain.mushtaq@aku.edu.
Aga Khan University Hospital · PKAga Khan University Hospital Nairobi · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although neurological manifestations such as headache and myalgias have been observed with COVID-19, presentation with more serious neurological illness is uncommon and rare. We report a case of a middle-aged woman who presented to the emergency department of a tertiary care hospital. Her clinical presentation was primarily neurological rather than the more common presentation with respiratory manifestations. She presented with generalised tonic-clonic seizures, along with history of undocumented low-grade fever and generalised body aches. The positive SARS-CoV-2 RT-PCR nasal swab, the cerebrospinal fluid analysis (lymphocytic pleocytosis) and electroencephalogram were consistent with viral encephalitis; brain imaging was unremarkable. This case highlights the variable presenting features of COVID-19 infection as patients can primarily present with neurological manifestations in the absence of significant respiratory symptoms. We believe it is important to recognise neurological disease associated with SARS-CoV-2 in patients with asymptomatic respiratory infection.

Indexed as

Brain DiseasesCOVID-19Status EpilepticusFemaleHumansMiddle AgedSARS-CoV-2SeizuresCOVID-19infection (neurology)infectious diseases

Identifiers

PMID35260396
PMCPMC8905954
OpenAlexW4220801651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.