Evidence map›Paper›PMID 35260135›Full record

ArticleBMC musculoskeletal disorders2022

Analysis of hydration and subchondral bone density on the viscoelastic properties of bovine articular cartilage.

Joseph P Crolla, Bernard M Lawless, Anna A Cederlund, Richard M Aspden, Daniel M Espino

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Development and experimental validation of a dynamic numerical model for human articular cartilage.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joseph P CrollaDeptment of Mechanical Engineering, University of Birmingham, Birmingham, B15 2TT, UK. J.P.Crolla@bham.ac.uk.
Bernard M LawlessDeptment of Mechanical Engineering, University of Birmingham, Birmingham, B15 2TT, UK.
Anna A CederlundCentre for Arthritis and Musculoskeletal Health, University of Aberdeen, AB25 2ZD, Foresterhill Aberdeen, UK.
Richard M AspdenCentre for Arthritis and Musculoskeletal Health, University of Aberdeen, AB25 2ZD, Foresterhill Aberdeen, UK.
Daniel M EspinoDeptment of Mechanical Engineering, University of Birmingham, Birmingham, B15 2TT, UK.
University of Birmingham · GBUniversity of Aberdeen · GB

Funding

Versus Arthritis 19971
6 · The paper itself

Abstract

backgroundArticular cartilage is known to be a viscoelastic material, however little research has explored the impact of cartilage water content and bone density on its viscoelasticity. This study aimed to isolate subchondral bone density and hydration of articular cartilage and analyse their effects on the viscoelastic properties of articular cartilage.

methodsDynamic mechanical analysis was used to test samples at frequencies of 1, 8, 12, 29, 49, 71, and 88 Hz. Synthetic bone material with densities of 663.7 kg/m

resultsSamples from eight bovine femoral heads were tested under a sinusoidal load. Storage stiffness was lower on the lower substrate density. Storage stiffness, though, increased as cartilage samples were dehydrated from a water content of 76% to 8.5%; decreasing again as the water content was further reduced. Loss stiffness was lower on a lower density substrate and decreased as the water content decreased.

conclusionsIn conclusions, a decrease in hydration decreases the loss stiffness, but a non-linear relationship between hydration and storage stiffness may exist. Additionally, higher BMD values led to greater storage and loss stiffnesses.

Indexed as

Bone DensityCartilage, ArticularAnimalsBiomechanical PhenomenaCattleElasticityFemur HeadHumansArticular cartilageBone densityHydrationLossStorageViscoelasticity

Identifiers

PMID35260135
PMCPMC8905800
OpenAlexW4220922328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.