Evidence map›Paper›PMID 35260039›Full record

ReviewRenal failure2022

Utilization of HCV viremic donors in kidney transplantation: a chance or a threat?

Paulina Czarnecka, Kinga Czarnecka, Olga Tronina, Teresa Baczkowska, Magdalena Durlik

Open access · goldAbstract readReviewVideo-Audio Media
In one paragraph

Review in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Renal Manifestations of Chronic Hepatitis C: A Review.Journal of clinical medicine · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Paulina CzarneckaDepartment of Transplant Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.
Kinga CzarneckaDepartment of Transplant Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.
Olga TroninaDepartment of Transplant Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.
Teresa BaczkowskaDepartment of Transplant Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.
Magdalena DurlikDepartment of Transplant Medicine, Nephrology and Internal Diseases, Medical University of Warsaw, Warsaw, Poland.
Medical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kidney transplantation is the treatment of choice in end-stage renal disease. The main issue which does not allow to utilize it fully is the number of organs available for transplant. Introduction of highly effective oral direct-acting antivirals (DAAs) to the treatment of chronic hepatitis C virus infection (HCV) enabled transplantation of HCV viremic organs to naive recipients. Despite an increasing number of reports on the satisfying effects of using HCV viremic organs, including kidneys, they are more often rejected than those from HCV negative donors. The main reason is the presence of HCV viremia and not the quality of the organ. The current state of knowledge points to the fact that a kidney transplant from an HCV nucleic acid testing positive (NAT+) donor to naive recipients is an effective and safe solution to the problem of the insufficient number of organs available for transplantation. It does not, however, allow to draw conclusions as to the long-term consequence of such an approach. This review analyzes the possibilities and limitations of the usage of HCV NAT + donor organs.

Indexed as

Kidney TransplantationAntiviral AgentsGraft RejectionHepatitis C, ChronicHumansKidneyTissue and Organ ProcurementViremiaAntiviral Agentsantiviral drugshepatitis Corgan donorsRenal transplantation

Identifiers

PMID35260039
PMCPMC8920354
OpenAlexW4220890303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.