Evidence map›Paper›PMID 35260004›Full record

SynthesisPalliative medicine2022

Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review.

Elin Baddeley, Mala Mann, Alison Bravington, Miriam J Johnson, David Currow, Fliss E M Murtagh, Elaine G Boland, George Obita, Alfred Oliver, Kathy Seddon and 3 more

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Palliative medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. High-quality phase 3 studies do not support the use of somatostatin analogues to reduce vomiting in malignant bowel obstruction.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Elin BaddeleyMarie Curie Palliative Care Research Centre, Cardiff University, Cardiff, UK.ORCID 0000-0002-7571-4820
Mala MannMarie Curie Palliative Care Research Centre, Cardiff University, Cardiff, UK.ORCID 0000-0002-2554-9265
Alison BravingtonWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.
Miriam J JohnsonWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.ORCID 0000-0001-6204-9158
David CurrowUniversity of Technology Sydney, Sydney, NSW, Australia.ORCID 0000-0003-1988-1250
Fliss E M MurtaghWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.ORCID 0000-0003-1289-3726
Elaine G BolandQueens Centre for Oncology and Haematology, Cottingham, Hull, UK.
George ObitaDove House Hospice, Hull, England, UK.
Alfred OliverNational Cancer Research Institute, Consumer Liaison Group; Trans-Humber Consumer Research Panel, London, UK.
Kathy SeddonMarie Curie Palliative Care Research Centre, Cardiff University, Cardiff, UK.
Annmarie NelsonMarie Curie Palliative Care Research Centre, Cardiff University, Cardiff, UK.
Jason W BolandWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, UK.ORCID 0000-0001-5272-3057
Simon I R NobleMarie Curie Palliative Care Research Centre, Cardiff University, Cardiff, UK.
Marie Curie · GBUniversity of Hull · GBNational Cancer Research Institute · GBTrinity House · GBUniversity of Technology Sydney · AU

Funding

Department of HealthMarie Curie MCRGS-20171220-8020
6 · The paper itself

Abstract

backgroundMalignant bowel obstruction occurs in up to 50% of people with advanced ovarian and 15% of people with gastrointestinal cancers. Evaluation and comparison of interventions to manage symptoms are hampered by inconsistent evaluations of efficacy and lack of agreed core outcomes. The patient perspective is rarely incorporated.

aimTo synthesise the qualitative data regarding patient, caregiver and healthcare professionals' views and experience of malignant bowel obstruction to inform the development of a core outcome set for the evaluation of malignant bowel obstruction.

designA qualitative systematic review was conducted, with narrative synthesis. The review protocol was registered prospectively (https://www.crd.york.ac.uk/prospero, CRD42020176393). DATA SOURCES: MEDLINE, EMBASE, CINAHL, PsycINFO and Scopus databases were searched for studies published between 2010 and 2021. Reference lists were screened for further relevant publications, and citation tracking was performed.

resultsNine papers were included, reporting on seven studies which described the views and experiences of malignant bowel obstruction through the perspectives of 75 patients, 13 caregivers and 62 healthcare professionals. Themes across the papers included symptom burden, diverse experiences of interventions, impact on patient quality of life, implications and trajectory of malignant bowel obstruction, mixed experience of communication and the importance of realistic goals of care.

conclusionSome of the most devastating sequelae of malignant bowel obstruction, such as pain and psychological distress, are not included routinely in its clinical or research evaluation. These data will contribute to a wider body of work to ensure the patient and caregiver perspective is recognised in the development of a core outcome set.

Indexed as

CaregiversIntestinal ObstructionDelivery of Health CareHealth PersonnelHumansQualitative ResearchQuality of Lifecancergastric outlet obstructionintestinal obstructionMalignant bowel obstructionneoplasmspalliative carequalitative researchsystematic review

Identifiers

PMID35260004
PMCPMC9174615
OpenAlexW4221090081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.