Evidence map›Paper›PMID 35259958›Full record

ArticleJournal of the Royal Society, Interface2022

Stabilization of antithetic control via molecular buffering.

Edward J Hancock, Diego A Oyarzún

Open access · greenAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Noise properties of adaptation-conferring biochemical control modules.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Regulation strategies for two-output biomolecular networks.Journal of the Royal Society, Interface · 2023
    Article
  5. Stabilization of antithetic control via molecular buffering.Journal of the Royal Society, Interface · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Edward J HancockSchool of Mathematics and Statistics, The University of Sydney, New South Wales 2006, Australia.ORCID 0000-0003-1606-9611
Diego A OyarzúnSchool of Informatics, The University of Edinburgh, Edinburgh, UK.
The Alan Turing Institute · GBThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key goal in synthetic biology is the construction of molecular circuits that robustly adapt to perturbations. Although many natural systems display perfect adaptation, whereby stationary molecular concentrations are insensitive to perturbations, its

Indexed as

Models, BiologicalSynthetic BiologyAcclimatizationAdaptation, PhysiologicalHomeostasisantithetic controlbiomolecular controlbufferingfeedback

Identifiers

PMID35259958
PMCPMC8905164
OpenAlexW4220658974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.