Evidence map›Paper›PMID 35259837›Full record

ArticleNeural regeneration research2022

Ubiquitin homeostasis disruption, a common cause of proteostasis collapse in amyotrophic lateral sclerosis?

Christen G Chisholm, Jeremy S Lum, Natalie E Farrawell, Justin J Yerbury

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Toxic mechanisms of amyloid oligomers and therapeutic strategies.Protein science : a publication of the Protein Society · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Christen G ChisholmIllawarra Health and Medical Research Institute; Molecular Horizons and School of Chemistry and Molecular Bioscience, Science Medicine and Health Faculty, University of Wollongong, Northfields Ave, Wollongong, NSW, Australia.
Jeremy S LumIllawarra Health and Medical Research Institute; Molecular Horizons and School of Chemistry and Molecular Bioscience, Science Medicine and Health Faculty, University of Wollongong, Northfields Ave, Wollongong, NSW, Australia.
Natalie E FarrawellIllawarra Health and Medical Research Institute; Molecular Horizons and School of Chemistry and Molecular Bioscience, Science Medicine and Health Faculty, University of Wollongong, Northfields Ave, Wollongong, NSW, Australia.
Justin J YerburyIllawarra Health and Medical Research Institute; Molecular Horizons and School of Chemistry and Molecular Bioscience, Science Medicine and Health Faculty, University of Wollongong, Northfields Ave, Wollongong, NSW, Australia.
Illawarra Health and Medical Research Institute · AUUniversity of Wollongong · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID35259837
PMCPMC9083156
OpenAlexW4220745203

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.