Evidence map›Paper›PMID 35259637›Full record

ArticleGait & posture2022

Acute effects of axial loading on postural control during walking and turning in people with multiple sclerosis: A pilot study.

Casey Little, Connor Moore, Emily Bean, Denise M Peters, Ryan S McGinnis, Susan L Kasser

Open access · greenAbstract read
In one paragraph

Article in Gait & posture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Casey LittleDepartment of Rehabilitation and Movement Science, University of Vermont, Burlington, USA.
Connor MooreDepartment of Rehabilitation and Movement Science, University of Vermont, Burlington, USA.
Emily BeanDepartment of Rehabilitation and Movement Science, University of Vermont, Burlington, USA.
Denise M PetersDepartment of Rehabilitation and Movement Science, University of Vermont, Burlington, USA.
Ryan S McGinnisDepartment of Electrical and Biomedical Engineering, University of Vermont, Burlington, VT, USA.
Susan L KasserDepartment of Rehabilitation and Movement Science, University of Vermont, Burlington, USA. Electronic address: Susan.Kasser@med.uvm.edu.
University of Vermont · US

Funding

Vermont Center for Cardiovascular and Brain HealthP20GM135007 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Diego Adrianzen Herrera · 2020 to 2026
$17.4M
NIGMS NIH HHS P20 GM135007
6 · The paper itself

Abstract

backgroundImpaired sensory integration is heavily involved in gait control and accentuates fall risk in individuals with multiple sclerosis (MS). While axial loading has been found beneficial, little is known about the effect of non-specific axial loads on gait parameters and mobility tasks in those with MS. RESEARCH QUESTION: What are the effects of non-specific axial loading via weighted vests on walking and turning in those with MS.

methodsTwelve participants with MS and eleven age- and gender-matched healthy controls participated in a cross-sectional study. All participants completed five trials of continuous walking with turns wearing weighted vests at 0%, 2%, 4%, 5%, and then 0% of their body weight. Gait parameters were measured using wireless inertial sensors. A 2 (group) x 5 (vest weight) multivariate analysis of variance (MANOVA) was performed to determine any significant differences between groups and across weighted vests for each gait variable. Post-hoc analysis and paired t-tests with corresponding effect sizes were also conducted.

resultsA significant between groups main effect was found for group (F (6100) = 14.74, p = .000) in multiple gait parameters (p < 0.05), although no significant main effect was found for weighted vest. Within group analyses indicated significantly increased cadence and gait speed across varying weighted vests for both MS and control groups (p < 0 >05). Increased vest weight from 0%PRE to 2% also had large effect on shortening double support time and increasing stride length in the MS group. SIGNIFICANCE: This study provided preliminary evidence that non-specific axial loads of varying weights appear to improve certain gait parameters. As such, this modality may offer mobility benefit and serve as an accessible home-based intervention alternative aimed at improving walking in individuals with MS.

Indexed as

Multiple SclerosisCross-Sectional StudiesGaitHumansPilot ProjectsPostural BalanceWalkingWeight-BearingBalanceGaitMultiple sclerosisSensory modulationTorso weighting

Identifiers

PMID35259637
PMCPMC9086176
OpenAlexW4214906364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.