Evidence map›Paper›PMID 35259196›Full record

ArticlePloS one2022

High mortality among hospitalized adult patients with COVID-19 pneumonia in Peru: A single centre retrospective cohort study.

Guiliana Mas-Ubillus, Pedro J Ortiz, Jorge Huaringa-Marcelo, Paola Sarzo-Miranda, Patricia Muñoz-Aguirre, Alejandra Diaz-Ramos, Kattia Arribasplata-Purizaca, Doris Mendoza, Juan Rojas-Poma, Cristian Marcelo-Ruiz and 3 more

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Guiliana Mas-UbillusDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Pedro J OrtizDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.ORCID 0000-0001-8071-8650
Jorge Huaringa-MarceloDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Paola Sarzo-MirandaDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Patricia Muñoz-AguirreDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Alejandra Diaz-RamosDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Kattia Arribasplata-PurizacaDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Doris MendozaDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Juan Rojas-PomaDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Cristian Marcelo-RuizDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Pedro Ayala-DiazDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Edwin Hidalgo-ArroyoDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.
Lourdes Tupia-CespedesDepartment of Emergency, Hospital Nacional Arzobispo Loayza, Cercado de Lima, Lima, Peru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeru is the country with the world's highest COVID-19 death rate per capita. Characteristics associated with increased mortality among adult patients with COVID-19 pneumonia in this setting are not well described.

methodsRetrospective, single-center cohort study including 1537 adult patients hospitalized with a diagnosis of SARS-CoV-2 pneumonia between May 2020 and August 2020 at a national hospital in Lima, Peru. The primary outcome measure was in-hospital mortality.

resultsIn-hospital mortality was 49.71%. The mean age was 60 ± 14.25 years, and 68.38% were males. We found an association between mortality and inflammatory markers, mainly leukocytes, D-dimer, lactate dehydrogenase, C-reactive protein and ferritin. A multivariate model adjusted for age, hypertension, diabetes mellitus, and corticosteroid use demonstrated that in-hospital mortality was associated with greater age (RR: 2.01, 95%CI: 1.59-2.52) and a higher level of oxygen requirement (RR: 2.77, 95%CI: 2.13-3.62). Conclusions: In-hospital mortality among COVID-19 patients in Peru is high and is associated with greater age and higher oxygen requirements.

Indexed as

AgedAge FactorsComorbidityCOVID-19C-Reactive ProteinFemaleFerritinsFibrin Fibrinogen Degradation ProductsHospitalizationHospital MortalityHumansMaleMiddle AgedPeruRespiration, ArtificialRetrospective StudiesC-Reactive ProteinFerritinsFibrin Fibrinogen Degradation Productsfibrin fragment D

Identifiers

PMID35259196
PMCPMC8903290

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.