Evidence map›Paper›PMID 35259169›Full record

ArticlePloS one2022

Optimization of COVID-19 vaccination and the role of individuals with a high number of contacts: A model based approach.

Tarcísio M Rocha Filho, José F F Mendes, Thiago B Murari, Aloísio S Nascimento Filho, Antônio J A Cordeiro, Walter M Ramalho, Fúlvio A Scorza, Antônio-Carlos G Almeida, Marcelo A Moret

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tarcísio M Rocha FilhoInternational Center for Condensed Matter Physics, Universidade de Brasília, Brasília, DF, Brazil.ORCID 0000-0002-7865-4085
José F F MendesDepartamento de Física & I3N, Universidade de Aveiro, Aveiro, Portugal.
Thiago B MurariCentro Universitário SENAI CIMATEC, Salvador, BA, Brazil.ORCID 0000-0001-5598-2679
Aloísio S Nascimento FilhoCentro Universitário SENAI CIMATEC, Salvador, BA, Brazil.
Antônio J A CordeiroCentro Universitário SENAI CIMATEC, Salvador, BA, Brazil.
Walter M RamalhoFCE and Núcleo de Medicina Tropical, Universidade de Brasília, Brasília, DF, Brazil.
Fúlvio A ScorzaDisciplina de Neurociência, Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, SP, Brazil.
Antônio-Carlos G AlmeidaUniversidade Federal de São João del-Rei (UFSJ), São João del-Rei, MG, Brazil.
Marcelo A MoretCentro Universitário SENAI CIMATEC, Salvador, BA, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report strong evidence of the importance of contact hubs (or superspreaders) in mitigating the current COVID-19 pandemic. Contact hubs have a much larger number of contacts than the average in the population, and play a key role on the effectiveness of vaccination strategies. By using an age-structures compartmental SEIAHRV (Susceptible, Exposed, Infected symptomatic, Asymptomatic, Hospitalized, Recovered, Vaccinated) model, calibrated from available demographic and COVID-19 incidence, and considering separately those individuals with a much greater number of contacts than the average in the population, we show that carefully choosing who will compose the first group to be vaccinated can impact positively the total death toll and the demand for health services. This is even more relevant in countries with a lack of basic resources for proper vaccination and a significant reduction in social isolation. In order to demonstrate our approach we show the effect of hypothetical vaccination scenarios in two countries of very different scales and mitigation policies, Brazil and Portugal.

Indexed as

Models, TheoreticalBrazilCOVID-19COVID-19 VaccinesHumansPortugalSARS-CoV-2VaccinationVaccine EfficacyCOVID-19 Vaccines

Identifiers

PMID35259169
PMCPMC8903293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.