Action mechanism of early cerebral injuries after spontaneous subarachnoid hemorrhage by silence Ghrelin and angiogenic factor with G-patch and FHA domain 1.

Jianxun Tang, Ligang Hu, Feng Long, Jie Zhang, Jingfeng Tang

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Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

–field-weighted citation impact, top 96% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jianxun TangDepartment of Cerebrovascular Disease, The Second Affiliated Hospital of Guilin Medical University, Guilin, China.

Ligang HuDepartment of Cerebrovascular Disease, The Second Affiliated Hospital of Guilin Medical University, Guilin, China.

Feng LongDepartment of Cerebrovascular Disease, General Medical College of Guilin Medical College, Guilin, China.

Jie ZhangDepartment of Cerebrovascular Disease, The Second Affiliated Hospital of Guilin Medical University, Guilin, China.

Jingfeng TangDepartment of Cerebrovascular Disease, The Second Affiliated Hospital of Guilin Medical University, Guilin, China.

Guilin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of the research was to investigate action mechanism of oxidative stress and cerebral injuries after subarachnoid hemorrhage (SAH) by Ghrelin and angiogenic factor G-patch and FHA domain 1 (Aggf1) and offer new research ideas to SAH clinical treatment and SAH-induced early cerebral injuries. SAH rat models were prepared by prechiasmatic anterior cistern injection. Specific Ghrelin and Aggf1 small interfering ribonucleic acid (siRNA) were designed and injected into silence Ghrelin or Aggf1 in rat left lateral ventricles. Rats were divided randomly into sham-operated (sham), SAH model, negative control siRNA, Ghrelin silence (Ghrelin

Indexed as

Subarachnoid HemorrhageAngiogenesis Inducing AgentsAnimalsApoptosisCaspase 3Disease Models, AnimalGhrelinGlutathione DisulfideProto-Oncogene Proteins c-aktRatsRats, Sprague-DawleyRNA, Small InterferingWaterAngiogenesis Inducing AgentsCaspase 3GhrelinGlutathione DisulfideProto-Oncogene Proteins c-aktRNA, Small InterferingWaterangiogenic factor with G-patch and FHA domain 1early cerebral injuriesGhrelinoxidative stresssubarachnoid hemorrhage

Identifiers

PMID35259055

DOI10.1080/21655979.2022.2037373

PMCPMC8974202

OpenAlexW4220787486

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.