Evidence map›Paper›PMID 35259020›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Juvenile hormone-induced histone deacetylase 3 suppresses apoptosis to maintain larval midgut in the yellow fever mosquito.

Sharath Chandra Gaddelapati, Najla M Albishi, Ramesh Kumar Dhandapani, Subba Reddy Palli

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Altered histone modifications inbioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Proteomics analysis of soluble secreted proteins ofFrontiers in cellular and infection microbiology · 2025
    Article
  11. Article
  12. HDAC1: An Essential and Conserved Member of the Diverse ZnInternational journal of molecular sciences · 2023
    Article
  13. NInsect biochemistry and molecular biology · 2023
    Article
  14. Article
  15. Article
  16. HDAC3 Knockdown Dysregulates Juvenile Hormone and Apoptosis-Related Genes inInternational journal of molecular sciences · 2022
    Article
  17. Article
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sharath Chandra GaddelapatiDepartment of Entomology, University of Kentucky, Lexington, KY 40546.ORCID 0000-0001-7787-0934
Najla M AlbishiDepartment of Entomology, University of Kentucky, Lexington, KY 40546.ORCID 0000-0002-3900-459X
Ramesh Kumar DhandapaniDepartment of Entomology, University of Kentucky, Lexington, KY 40546.
Subba Reddy PalliDepartment of Entomology, University of Kentucky, Lexington, KY 40546.ORCID 0000-0002-0873-3247
University of Kentucky · US

Funding

Molecular Analysis of Juvenile Hormone ActionR01GM070559 · NIGMS · UNIVERSITY OF KENTUCKY · PI PALLI, SUBBA R · 2005 to 2024
$4.1M
NIGMS NIH HHS R01 GM070559
6 · The paper itself

Abstract

SignificanceJuvenile hormone (JH), a sesquiterpenoid, regulates many aspects of insect development, including maintenance of the larval stage by preventing metamorphosis. In contrast, ecdysteroids promote metamorphosis by inducing the

Indexed as

ApoptosisAedesAnimalsDigestive SystemEcdysoneGene Expression RegulationGene Knockdown TechniquesHistone Deacetylase 3Histone DeacetylasesHistonesJuvenile HormonesLarvaPupaEcdysoneHistone Deacetylase 3Histone DeacetylasesHistonesJuvenile HormonesAedes aegyptiapoptosisepigeneticshistone deacetylasemidgut-remodeling

Identifiers

PMID35259020
PMCPMC8931318
OpenAlexW4220762399

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.