Evidence map›Paper›PMID 35258994›Full record

Observational studyJournal of clinical oncology : official journal of the American Society of Clinical Oncology2022

Lung Cancer Diagnosed Through Screening, Lung Nodule, and Neither Program: A Prospective Observational Study of the Detecting Early Lung Cancer (DELUGE) in the Mississippi Delta Cohort.

Raymond U Osarogiagbon, Wei Liao, Nicholas R Faris, Meghan Meadows-Taylor, Carrie Fehnel, Jordan Lane, Sara C Williams, Anita A Patel, Olawale A Akinbobola, Alicia Pacheco and 12 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
10.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Article
  7. Over- and underscreening for lung cancer.Translational lung cancer research · 2026
    Review
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  17. Frontiers in medicine · 2026
    Article
  18. Incidental Pulmonary Nodules: What Should We Do in 2026?Respiration; international review of thoracic diseases · 2026
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 1 institution in 1 country.

Raymond U OsarogiagbonMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.ORCID 0000-0001-9427-8545
Wei LiaoMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Nicholas R FarisMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Meghan Meadows-TaylorMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Carrie FehnelMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Jordan LaneMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Sara C WilliamsMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Anita A PatelMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Olawale A AkinbobolaMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Alicia PachecoMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Amanda EppersonMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Joy LuttrellMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Denise McCoyMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Laura McHughMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Raymond SignoreMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Anna M BishopMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Keith TonkinMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Robert OpticanMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Jeffrey WrightMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.ORCID 0000-0003-0591-1527
Todd RobbinsMultidisciplinary Thoracic Oncology Program, Baptist Cancer Center, Memphis, TN.
Meredith A RayDivision of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN.ORCID 0000-0001-5312-3774
Matthew P SmeltzerDivision of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN.ORCID 0000-0003-1366-9267
University of Memphis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLung cancer screening saves lives, but implementation is challenging. We evaluated two approaches to early lung cancer detection-low-dose computed tomography screening (LDCT) and program-based management of incidentally detected lung nodules.

methodsA prospective observational study enrolled patients in the early detection programs. For context, we compared them with patients managed in a Multidisciplinary Care Program. We compared clinical stage distribution, surgical resection rates, 3- and 5-year survival rates, and eligibility for LDCT screening of patients diagnosed with lung cancer.

resultsFrom 2015 to May 2021, 22,886 patients were enrolled: 5,659 in LDCT, 15,461 in Lung Nodule, and 1,766 in Multidisciplinary Care. Of 150, 698, and 1,010 patients diagnosed with lung cancer in the respective programs, 61%, 60%, and 44% were diagnosed at clinical stage I or II, whereas 19%, 20%, and 29% were stage IV (

conclusionLDCT and Lung Nodule Programs are complementary, expanding access to early lung cancer detection and curative treatment to different-risk populations. Implementing Lung Nodule Programs may alleviate emerging disparities in access to early lung cancer detection.

Indexed as

Lung NeoplasmsEarly Detection of CancerHumansLungMass ScreeningTomography, X-Ray Computed

Identifiers

PMID35258994
PMCPMC9242408
OpenAlexW4220683514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.