Evidence map›Paper›PMID 35258819›Full record

ArticleCJEM2022

The emergency department incidence of incidental intracranial aneurysm on computed tomography angiography (EPIC-ACT) study.

Charles K H Wong, Connor M O'Rielly, Ben Sheppard, Gregory Beller

Abstract read
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In one paragraph

Article in CJEM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Imaging of Intracranial Saccular Aneurysms.Stroke (Hoboken, N.J.) · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Charles K H WongDepartment of Emergency Medicine, Cumming School of Medicine, University of Calgary, 7007 14 St SW, Calgary, AB, T2V 1P9, Canada. ckhwong@ucalgary.ca.ORCID http://orcid.org/0000-0002-1387-2583
Connor M O'RiellyDepartment of Emergency Medicine, Cumming School of Medicine, University of Calgary, 7007 14 St SW, Calgary, AB, T2V 1P9, Canada.
Ben SheppardDepartment of Emergency Medicine, Cumming School of Medicine, University of Calgary, 7007 14 St SW, Calgary, AB, T2V 1P9, Canada.
Gregory BellerDepartment of Emergency Medicine, Cumming School of Medicine, University of Calgary, 7007 14 St SW, Calgary, AB, T2V 1P9, Canada.
University of Calgary · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubarachnoid hemorrhage has been traditionally ruled-out in the emergency department (ED) through computed tomography (CT) followed by lumbar puncture if indicated. Mounting evidence suggests that non-contrast CT with CT angiography (CTA) can safely rule-out subarachnoid hemorrhage and obviate the need for lumbar puncture, but adoption of this approach is hindered by concerns of identifying incidental aneurysms. This study aims to estimate the incidence of incidental aneurysms identified on CTA head and neck in an ED population.

methodsThis was a health records review of all patients ≥ 18 years who underwent CTA head and neck for any indication at four large urban tertiary care EDs over a 3 month period. Patients were excluded if they underwent CT venogram only, had previously documented intracranial aneurysms, or had intracranial hemorrhage with or without aneurysm. Imaging reports were reviewed by two independent physicians before extracting relevant demographic (age, sex), clinical (CTAS level, CEDIS primary complaint) and radiographic (number, size, and location of aneurysms) information. The incidence rate of incidental aneurysms was calculated.

resultsA total of 1089 CTA studies were reviewed with a 3.3% (95% CI 2.3-4.6) incidence of incidental intracranial aneurysms. The median size of incidental aneurysms was 4 mm (0.7-11) and 10 (27.7%) patients had multiple aneurysms. Patients with incidental aneurysms did not differ based on mean age, sex, and CTAS levels.

conclusionsThe "risk" of discovering an incidental aneurysm is 3.3%. Clinicians should not be deterred from using CTA in the appropriate clinical settings. These estimates can inform shared decision-making conversations with patients when comparing subarachnoid hemorrhage rule-out options.

Indexed as

Intracranial AneurysmSubarachnoid HemorrhageCerebral AngiographyComputed Tomography AngiographyEmergency Service, HospitalHumansIncidenceSensitivity and SpecificityTomography, X-Ray ComputedComputed tomography angiographyIncidental aneurysms

Identifiers

PMID35258819
OpenAlexW4220920947

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.