Evidence map›Paper›PMID 35258752›Full record

SynthesisJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2022

Effect of weight loss on recurrence of atrial fibrillation after ablative therapy: a systematic review and meta-analysis.

Dae Yong Park, Seokyung An, Mukunthan Murthi, Ajoe John Kattoor, Amandeep Kaur, Venkatesh Ravi, Henry D Huang, Aviral Vij

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Comparing GLP-1 agonists versus other weight loss interventions on risk of atrial fibrillation recurrence after catheter ablation: a meta-analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
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  7. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dae Yong ParkDepartment of Medicine, John H. Stroger Jr Hospital of Cook County, Chicago, IL, USA.
Seokyung AnDepartment of Biomedical Science, Seoul National University Graduate School, Seoul, South Korea.
Mukunthan MurthiDepartment of Medicine, John H. Stroger Jr Hospital of Cook County, Chicago, IL, USA.
Ajoe John KattoorDivision of Cardiology, Cook County Health, Chicago, IL, USA.
Amandeep KaurDepartment of Pathology, McGaw Medical Center of Northwestern University, Chicago, IL, USA.
Venkatesh RaviWarren Clinic Cardiology, Saint Francis Health System, Tulsa, OK, USA.
Henry D HuangDivision of Cardiology, Rush Medical College, Chicago, IL, USA.
Aviral VijDivision of Cardiology, Cook County Health, Chicago, IL, USA. aviral.vij@cookcountyhhs.org.ORCID http://orcid.org/0000-0003-1381-5834

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLandmark trials have shown superiority of ablative therapy over medical therapy in certain subpopulation with atrial fibrillation (AF). Previous studies have demonstrated an association between weight loss and reduced rates of recurrence of AF after ablation. The objective of this study is to determine if weight loss reduces the recurrence of AF after ablation.

methodsAn extensive literature search and systematic review of studies of weight loss on recurrence of AF after ablative therapy was performed. Risk ratio (RR) and 95% confidence intervals were measured for weight loss group versus control group in each study, and comparative analysis as well as subgroup analysis was made.

resultsEight studies with a total of 1,425 patients were included. Overall, studies of patients who lost weight demonstrated lower recurrence of AF (RR 0.35; 95% CI 0.18-0.67). However, subgroup analysis of studies which included patients who lost ≥10% weight loss from baseline showed lower recurrence of AF (RR 0.18; 95% 0.03-0.89), whereas studies which included patients with <10% weight loss did not (RR 1.00; 95% 0.51-1.96). Studies of patients who had less than 12-month history of AF (RR 0.24; 95% CI 0.11-0.57) and those who lost weight prior to ablation (RR 0.40; 95% CI 0.20-0.79) also had lower recurrence of AF.

conclusionWeight loss is associated with lower long-term recurrence of AF after ablative therapy. Studies of patients with ≥10% weight loss, less than 12-month history of AF, and weight loss prior to ablation experience lower recurrence of AF.

Indexed as

Atrial FibrillationCatheter AblationHumansOdds RatioRecurrenceTreatment OutcomeWeight LossAblationAtrial fibrillationObesityRecurrenceWeight lossWeight reduction

Identifiers

PMID35258752

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.