Evidence map›Paper›PMID 35258742›Full record

ReviewNanoscale research letters2022

Photodynamic Therapeutic Effect of Nanostructured Metal Sulfide Photosensitizers on Cancer Treatment.

Daysi Diaz-Diestra, Hanna Madadi Gholipour, Marjan Bazian, Bibek Thapa, Juan Beltran-Huarac

Open access · goldAbstract readReview
In one paragraph

Review in Nanoscale research letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Recent Trends in Biomedical Applications of CuInternational journal of nanomedicine · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Daysi Diaz-DiestraDepartment of Chemistry, University of Puerto Rico, San Juan, PR, 00931, USA.
Hanna Madadi GholipourDepartment of Physics, Babol Noshirvani University of Technology, 47148, Babol, Iran.
Marjan BazianDepartment of Physics, Alzahra University, 19938, Tehran, Iran.
Bibek ThapaAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Juan Beltran-HuaracDepartment of Physics, Howell Science Complex, East Carolina University, Greenville, NC, 27858, USA. beltranhuaracj19@ecu.edu.
Advanced Imaging Research (United States) · USAlzahra University · IRBabol Noshirvani University of Technology · IREast Carolina University · USUniversity of Puerto Rico System · PR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) utilizes photosensitizers (PSs) to produce reactive oxygen species (ROSs) upon irradiation, which causes the shutdown of vessels and deprives the tumor of nutrients and oxygen, and in turn induces adverse effects on the immune system. However, significant efforts are needed to increase the efficiency in PDT in terms of light delivery to specific PSs for the clinical treatment of tumors located deep under the skin. Even though PDT offers a disease site-specific treatment modality, current efforts are directed to improve the solubility (in body fluids and injectable solvents), photostability, amphiphilicity (for tissue penetration), elimination, and systemic toxicity of traditional PSs based on porphyrin derivatives. Nanostructured materials show promising features to achieve most of such combined efforts. They can be artificially engineered to carry multiple theranostic agents onto targeted tumor sites. However, recent studies on photosensitive Cd-based nanostructures, mostly used in PDT, indicate that leeching of Cd

Indexed as

Cancer treatmentMetal sulfidesPhotodynamic therapyPhotosensitizers

Identifiers

PMID35258742
PMCPMC8904679
OpenAlexW4220864877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.