Evidence map›Paper›PMID 35258641›Full record

SynthesisEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2022

Shock index as a predictor for mortality in trauma patients: a systematic review and meta-analysis.

Malene Vang, Maria Østberg, Jacob Steinmetz, Lars S Rasmussen

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06415006 (Can Shock Indices Be Prognostic Indicators in Sepsis/Septic Shock?), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06415006 completednot on this map

Can Shock Indices Be Prognostic Indicators in Sepsis/Septic Shock?

TypeobservationalSponsorBaşakşehir Çam & Sakura City HospitalRan2012 to 2024Enrolled1,522ConditionsShock, Septic, Hemodynamic InstabilityArmsMeasurement of hemodynamic parameters.
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Peripheral perfusion index as a predictor of severe shock in trauma patients: a prospective observational study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Observational
  3. Article
  4. Article
  5. Article
  6. [Construction of an Early-stage Risk Prediction Model for Trauma-Induced Coagulopathy].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Factors associated with a positive shock index in the prehospital setting after major trauma.Scandinavian journal of trauma, resuscitation and emergency medicine · 2025
    Article
  13. Article
  14. Predictive factors of mortality in patients with abdominal trauma.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Evaluation of pediatric trauma score and pediatric age-adjusted shock index in pediatric patients admitted to the hospital after an earthquake.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Malene VangDepartment of Anesthesia and Trauma Centre, Centre of Head and Orthopaedics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. malene.vang.koefoed.nielsen.01@regionh.dk.ORCID http://orcid.org/0000-0001-7012-8227
Maria ØstbergDepartment of Anesthesia and Trauma Centre, Centre of Head and Orthopaedics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Jacob SteinmetzDepartment of Anesthesia and Trauma Centre, Centre of Head and Orthopaedics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Lars S RasmussenDepartment of Anesthesia and Trauma Centre, Centre of Head and Orthopaedics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe primary aim was to determine whether a shock index (SI) ≥ 1 in adult trauma patients was associated with increased in-hospital mortality compared to an SI < 1.

methodsThis systematic review including a meta-analysis was performed in accordance with the PRISMA guidelines. EMBASE, MEDLINE, and Cochrane Library were searched, and two authors independently screened articles, performed the data extraction, and assessed risk of bias. Studies were included if they reported in-hospital, 30-day, or 48-h mortality, length of stay, massive blood transfusion or ICU admission in trauma patients with SI recorded at arrival in the emergency department or trauma center. Risk of bias was assessed using the Newcastle-Ottawa Scale, and the strength and quality of the body of evidence according to GRADE. Data were pooled using a random effects model. Inter-rater reliability was assessed with Cohen's kappa.

resultsWe screened 1350 citations with an inter-rater reliability of 0.90. Thirty-eight cohort studies were included of which 14 reported the primary outcome. All studies reported a significant higher in-hospital mortality in adult trauma patients with an SI ≥ 1 compared to those having an SI < 1. Twelve studies involving a total of 348,687 participants were included in the meta-analysis. The pooled risk ratio (RR) of in-hospital mortality was 4.15 (95% CI 2.96-5.83). The overall quality of evidence was low.

conclusionsThis systematic review found a fourfold increased risk of in-hospital mortality in adult trauma patients with an initial SI ≥ 1 in the emergency department or trauma center.

Indexed as

ShockAdultEmergency Service, HospitalHospital MortalityHumansReproducibility of ResultsTrauma CentersEmergency departmentMassive blood transfusionMortalityShock indexTrauma

Identifiers

PMID35258641
OpenAlexW4221110977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.