Evidence map›Paper›PMID 35258639›Full record

ReviewPediatric cardiology2022

Cardiac Complications Associated with COVID-19, MIS-C, and mRNA COVID-19 Vaccination.

Stephanie E Chin, Sejal M Bhavsar, Andrew Corson, Zelda J Ghersin, Hannah S Kim

Open access · bronzeAbstract readReview
In one paragraph

Review in Pediatric cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Long COVID in children and young people: then and now.Current opinion in infectious diseases · 2025
    Review
  4. Review
  5. Article
  6. Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025
    Review
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Distinct Features of Vascular Diseases in COVID-19.Journal of inflammation research · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stephanie E ChinK. Hovnanian Children's Hospital at Jersey Shore University Medical Center, Neptune, NJ, USA. schin@alpertzalescastro.com.
Sejal M BhavsarJoseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, NJ, USA.
Andrew CorsonK. Hovnanian Children's Hospital at Jersey Shore University Medical Center, Neptune, NJ, USA.
Zelda J GhersinK. Hovnanian Children's Hospital at Jersey Shore University Medical Center, Neptune, NJ, USA.
Hannah S KimJoseph M. Sanzari Children's Hospital at Hackensack University Medical Center, Hackensack, NJ, USA.
Jersey Shore University Medical Center · USCenter for Discovery · USHackensack University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 vaccine is now approved for individuals greater than 5 years of age, but vaccination rates remain lower than expected in the pediatric age group. Misinformation and widespread reporting of vaccine-related myocarditis are contributing to vaccine hesitancy. When compared to severe cardiac complications that are associated with COVID-19, vaccine-related myocarditis has a milder presentation, is easily treated, and has a good prognosis. Acute COVID-19 has been associated with higher rates of myocarditis and myocardial injury. Multisystem inflammatory syndrome in children occurs weeks after initial infection with SARS-CoV-2 and can be associated with severe cardiovascular complications and death. Cardiac complications associated with acute COVID-19 and MIS-C are more severe and occur more frequently than myocarditis after mRNA COVID-19 vaccination. Furthermore, some of the academic and social disruptions caused by the pandemic expect to be eased by widespread vaccination. For all these reasons, COVID-19 vaccination is strongly recommended for all eligible age groups.

Indexed as

COVID-19COVID-19 VaccinesChildHumansRNA, MessengerSARS-CoV-2Systemic Inflammatory Response SyndromeVaccinationCOVID-19 VaccinesRNA, MessengerCOVID-19MyocarditisVaccination

Identifiers

PMID35258639
PMCPMC8902276
OpenAlexW4220994431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.