ArticleTranslational vision science & technology2022
Corneal Epithelial Mapping Characteristics in Normal Eyes Using Anterior Segment Spectral Domain Optical Coherence Tomography.
Article in Translational vision science & technology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 23 citations in OpenAlex.
- Changes in corneal epithelial remodeling and associated factors in highly myopic patients after FS-LASIK.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Comparative analysis of epithelial remodeling after photorefractive keratectomy and keratorefractive lenticule extraction for myopia.Indian journal of ophthalmology · 2026Article
- Meesmann Corneal Dystrophy with Epithelial Basement Membrane Abnormalities: Clinical and Genetic Analysis of Two Families with Novel and Known Mutations inInternational journal of molecular sciences · 2026Article
- Corneal epithelium is altered in keratoconus and forme fruste keratoconus.Scientific reports · 2025Article
- Spatiotemporal single-cell analysis elucidates the cellular and molecular dynamics of human cornea aging.Genome medicine · 2025Article
- Variability in Corneal and Epithelial Pachymetry: A Comparison of Optopol Revo 130 and Optovue RTV XR Avanti in Healthy Patients.Journal of clinical medicine · 2025Article
- Determining the Relationship Between Regional Epithelial Thickness, Corneal Toricity, and Corneal Power in Normal Corneas.Journal of refractive surgery (Thorofare, N.J. : 1995) · 2025Article
- Normative distribution of corneal epithelial thickness on 9-mm OCT maps.Frontiers in medicine · 2025Article
- Effect of Age and Gender on Corneal Epithelial Thickness in Refractive Surgery Candidates.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Article
- Blepharoptosis and corneal epithelial thickness alterations, is there any relation?BMC ophthalmology · 2024Article
- Transepithelial Photorefractive Keratectomy-Review.Vision (Basel, Switzerland) · 2024Review
- Evaluation of dry eye disease and corneal epithelial mapping in patients with lower eyelid ectropion.International ophthalmology · 2024Article
- Corneal stromal mapping characteristics in normal corneas using anterior segment SD-OCT.Frontiers in medicine · 2024Article
- Corneal Epithelial Thickness Mapping: A Major Review.Journal of ophthalmology · 2024Review
- The Effect of Upper Eyelid Blepharoplasty on Corneal Tomography and Epithelial Profile.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Corneal Epithelial Thickness in Normal Corneas with Low and High Toricity.Journal of current ophthalmologyArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The detailed mapping characteristics of the corneal epithelial thickness (CET) in normal eyes from a Middle Eastern population were investigated in relation to age, sex, intraocular pressure, and keratometric power (K). Methods: A retrospective cross-sectional and analytical study was conducted using spectral domain optical coherence tomography (OCT). We calculated the CET in 124 subjects in 17 zones within a 6 mm circle. Exclusion criteria included subjects with dry eyes, keratoconus, previous eye surgery, glaucoma, and irregular corneas. Results: A total of 124 individuals was composed of 64 males and 60 females. The mean age of this population was 45.52, ranging from 18 to 79 years. The central CET was thicker in the central 2 mm than the other zones of the cornea except the nasal, inferior-nasal, inferior and inferior-temporal zones, respectively. Males have thicker CET than females in all zones except in the peripheral nasal zone. We found a positive and significant correlation between age and CET in the central, superior-peripheral, inferior-paracentral, and inferior-temporal paracentral zones. Additionally, a medium-positive correlation was detected between increasing age and the variability of epithelial spectral domain in different zones. No link between CET and intraocular pressure was found. Conclusions: This study analyzed 17 CET zones within the central 6 mm, where the central epithelium is resistant to aging. The CET was thinner superiorly than inferiorly. This may help in decision-making in refractive procedures and in the prediction of corneal diseases. Translational Relevance: OCT novel algorithms are noninvasive methods for measuring CET and have been demonstrated to be useful in refractive surgery planning and follow-up, as well as a robust tool for diagnosing potential corneal ectasia.
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