Evidence map›Paper›PMID 35258395›Full record

ArticleBioengineered2022

Has_circ_0008583 modulates hepatocellular carcinoma progression through the miR-1301-3p/METTL3 pathway.

Fenfen Wang, Zhengyuan Xie, Nuobei Zhang, Hao Ding, Kai Xiong, Li Guo, Hongyan Huang, Zhili Wen

RetractedAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. METTL3: a multifunctional regulator in diseases.Molecular and cellular biochemistry · 2025
    Review
  2. Review
  3. Review
  4. New insights into the regulation of METTL3 and its role in tumors.Cell communication and signaling : CCS · 2023
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Fenfen WangDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.
Zhengyuan XieDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.
Nuobei ZhangDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.
Hao DingDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.
Kai XiongDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.
Li GuoDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.
Hongyan HuangDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.
Zhili WenDepartment of Gastroenterology, The Second Affiliated Hospital of Nanchang University, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Has_circ_0008583 is reported to be involved in the progression of hepatocellular carcinoma (HCC), while its biological role in HCC remains unclear. Here, the qRT-PCR was used to detect the expression of has_circ_0008583. The CCK-8 kit was performed to measure cell proliferation. The cell migration and invasion were evaluated by Transwell. A dual-luciferase reporter assay was performed to confirm the target combination between the genes in has_circ_0008583/miR-1301-3p/METTL3 axis. The

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicroRNAsAnimalsCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansMethyltransferasesMiceRNA, CircularMethyltransferasesMETTL3 protein, humanMettl3 protein, mouseMicroRNAsMIRN1301 microRNA, humanRNA, CircularHas_circ_0008583Hepatocellular carcinomaMETTL3miR-1301-3p

Identifiers

PMID35258395
PMCPMC8805961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.